LANOXIN PG 0.0625mg Price

Overview

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This medicine contains an important and useful components, as it consists of
Digoxinis available in the market in concentration

Name

Digoxin

Precaution

Cardiac dysrhythmias, hypokalaemia, hypertension, IHD, hypercalcaemia, hypomagnesaemia, electroconversion, chronic cor pulmonale, aortic valve disease, acute myocarditis, congestive cardiomyopathies, constrictive pericarditis, heart block, elderly, renal impairment, abnormalities in thyroid function; pregnancy. IV digoxin can only be given to patients who have not received cardiac glycosides in the preceding 2 wk. Lactation: Drug enters breast milk; use with caution (American Academy of Pediatrics committee states, "compatible with nursing")

Indication

Heart failure, Supraventricular arrhythmias, Atrial fibrillation and Atrial flutter

Contra indication

Digitalis toxicity, ventricular tachycardia/fibrillation, obstructive cardiomyopathy. Arrhythmias due to accessory pathways (e.g. Wolff-Parkinson-White syndrome).

Side Effect

1-10% Dizziness (4.9%),Mental disturbances (4.1%),Diarrhea (3.2%),Headache (3.2%),Nausea (3.2%),Vomiting (1.6%),Maculopapular rash (1.6%) <1% Anorexia,Cardiac dysrhythmia,Arrhythmia in children (consider a toxicity) Frequency Not Defined Visual disturbance (blurred or yellow vision),Heart block (1°/2°/3°),Asystole,Tachycardia Potentially Fatal: Cardiac arrhythmias in combination with heart block.

Pregnancy Category ID

3

Mode of Action

Digoxin is a cardiac glycoside which has positive inotropic activity characterized by an increase in the force of myocardial contraction. It also reduces the conductivity of the heart through the atrioventricular (AV) node. Digoxin also exerts direct action on vascular smooth muscle and indirect effects mediated primarily by the autonomic nervous system and an increase in vagal activity.

Interaction

Effectiveness reduced by phenytoin, neomycin, sulphasalazine, kaolin, pectin, antacids and in patients receiving radiotherapy. Metoclopramide may alter the absorption of solid dosage forms of digoxin. Blood levels increased by calcium channel blockers, spironolactone, quinidine and calcium salts. Potentially Fatal: Electrolyte imbalances such as hypokalaemia and hypomagnesemia (e.g. admin of potassium-losing diuretics, corticosteroids) can increase the risk of cardiac toxicity.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration