ACULAR LS 0.4% Ophthalmic Solution price in UAE

Overview

Welcome to Dwaey, specifically on ACULAR LS 0.4% Ophthalmic Solution Eye Drops (Solution) page.
This medicine contains an important and useful components, as it consists of Ketorolac trometamol.
ACULAR LS 0.4% Ophthalmic Solution is available in the market in concentration 4mg/ml and in the form of Eye Drops (Solution).

ALLERGAN PHARMACEUTICALS, INC. is the producer of ACULAR LS 0.4% Ophthalmic Solution and it is imported from USA, The most popular alternatives of ACULAR LS 0.4% Ophthalmic Solution are listed downward .

Mode Of Action

Ketorolac inhibits prostaglandin synthesis by decreasing the activity of the cyclooxygenase enzyme.

Indication

Moderate to severe pain

Precaution

Elderly, patients weighing <50 kg, hepatic dysfunction, heart failure, predisposition to reduced blood volume or renal blood flow. Mild renal impairment; monitor renal function closely. Lactation: Drug excreted in breast milk with multiple doses; use contraindicated

Side Effects

>10% Headache (17%)
Somnolence (3-14%)
Dyspepsia (12-13%)
GI pain (12-13%)
Nausea (12-13%) 1-10% Diarrhea (3-9%)
Dizziness (3-9%)
Pruritus (3-9%)
Edema (1-3%)
Increased blood urea nitrogen (BUN) (3%)
Constipation (<3%)
Purpura (<3%)
Increased serum creatinine (2%)
Drowsiness (6%)
Hypertension (4%) <1% Abnormal thinking
Anaphylaxis
Blurred vision
Bronchospasm
Cholestatic jaundice
Depression
Difficulty in concentration
Dysgeusia
Euphoria
Hemolytic-uremic syndrome
Hepatitis
Hyperkalemia
Hyponatremia
Hypotension
Increased liver function test values
Insomnia
Laryngeal/lingual edema
Liver failure
Melena
Nervousness
Oliguria
Pallor
Peptic ulcer
Rash
Rectal bleeding
Stomatitis
Urinary frequency
Urinary retention
Vasodilation Potentially Fatal: Anaphylaxis. Severe skin reactions. MI
stroke
GI bleeding.

Contra indication

Hypersensitivity to aspirin or other NSAIDs, asthma. Hypovolaemia or dehydration. Do not give postoperatively to patients with high risk of haemorrhage. History of peptic ulcer or coagulation disorders. Nasal polyps, angioedema, bronchospasm. Labour. Moderate to severe renal impairment. GI bleeding, cerebrovascular bleeding. As prophylactic analgesic before surgery. Pregnancy, lactation.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Pregnancy category: C; D in third trimester (may cause premature closure of ductus arteriosus)

Interaction

May reduce effects of antihypertensives eg ACE inhibitors or angiotensin II receptor antagonists (AIIA). Increased risk of renal toxicity with ACE inhibitors, diuretics. Increased adverse effects with aspirin or other NSAIDs. Hallucinations may occur when used with fluoxetine, thiothixene, alprazolam. Potentially Fatal: Increased risk of GI bleeding with warfarin. May increase toxicity of methotrexate (MTX) and lithium. Increased plasma concentrations with probenecid.