Active Substance: Cephaloridin.
Overview
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This medicine contains an important and useful components, as it consists of
Cephaloridinis available in the market in concentration
Cephradine
Renal impairment; history of penicillin sensitivity; pregnancy; lactation.
Pneumonia, Pharyngitis, Susceptible infections, Otitis media, Skin and Skin-Structure Infections, Rheumatic fever, Tonsillitis, Respiratory tract infections, Urinary tract infections, Surgical Prophylaxis, Genitourinary tract infections, Acute prostatitis
Hypersensitivity to cefradine or other cephalosporins; porphyria.
Diarrhoea, nausea, vomiting; leukopenia, neutropenia, eosinophilia, rash, pruritus; joint pain; increased BUN and creatine; dizziness. Potentially Fatal: Pseudomembranous colitis.
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Cefradine is a 1st generation cephalosporin which inhibits the final transpeptidation step of the peptidoglycan synthesis in bacterial cell wall by binding to one or more of the penicillin-binding proteins (PBPs), thus arresting cell wall synthesis leading to bacterial cell death.
Increased risk of nephrotoxicity w/ loop diuretics. Decreased renal clearance w/ probenecid.
Information not available