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ISOKET 10 Price

Active Substance: Isosorbide dinitrate.

33
UAD , based on 7541 reviews.
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Overview

Welcome to Dwaey, specifically on ISOKET 10 page.
This medicine contains an important and useful components, as it consists of
Isosorbide dinitrateis available in the market in concentration

Name

Isosorbide Dinitrate

Precaution

Raised intracranial pressure, hypotension, hypovolaemia. Mitral valve prolapse, arterial hypoxaemia, glaucoma, elderly, hypothyroidism, malnutrition, pregnancy, lactation Lactation: Unknown whether drug is distributed into breast milk

Indication

Angina, Percutaneous transluminal coronary angioplasty

Contra indication

Severe hypotension or anaemia, hypovolaemia, heart failure due to obstruction, or raised intracranial pressure due to head trauma or cerebral haemorrhage.

Side Effect

Cardiovascular: Rebound hypertension (uncommon), syncope, unstable angina flushing, hypotension/orthostatic hypotension, lightheadedness, palpitations, tachyarrhythmia Central nervous system (CNS): Dizziness, headache, restlessness, weakness Gastrointestinal (GI): Nausea Hematologic: Methemoglobinemia (infrequent) Potentially Fatal: Severe hypotension, circulatory collapse.

Pregnancy Category ID

3

Mode of Action

Isosorbide dinitrate relaxes vascular smooth muscles by stimulating cyclic-GMP. It decreases left ventricular pressure (preload) and arterial resistance (afterload).

Interaction

Increased hypotensive effects with alcohol or vasodilators. Marked orthostatic hypotension may occur when used with calcium channel blockers. Vasodilatory effect may be reduced with dihydroergotamine. Ergotamine effects may be enhanced. Reduced effectiveness of sublingual form with disopyramide. Potentially Fatal: Significant hypotension may occur with phosphodiesterase-5 inhibitors.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration

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