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HEMOCLAR Price

Active Substance: Pentosan sulphuric ester.

30
UAD , based on 7541 reviews.
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Overview

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This medicine contains an important and useful components, as it consists of
Pentosan sulphuric esteris available in the market in concentration

Name

Pentosan Polysulphate Sodium

Precaution

Patients with spleen disorders, hepatic or renal impairment. Monitor platelet counts during treatment. To discontinue treatment if thrombocytopenia occurs. Caution when used in patients with haemorrhagic blood disorders, thrombocytopenia, peptic ulcer disease, cerebrovascular disorders, bacterial endocarditis, severe hypertension or oesophageal varices. Recent surgery at sites where haemorrhage would be an especial risk. Safety not established in children <16 yr. Patients should be monitored every 3 mth; risks and benefits after 6 mth of treatment not known. Pregnancy; lactation. Lactation: not known if excreted in breast milk, use caution

Indication

Interstitial cystitis, Nocturia, Painful bladder syndrome, Dyspareunia

Contra indication

Patients who are haemorrhaging. Serious renal or hepatic impairment. Not to be given via IM inj.

Side Effect

1-10% Alopecia (4%),Diarrhea (4%),Nausea (4%),Headache (3%),Abdominal pain (2%),Indigestion (2%)

Pregnancy Category ID

2

Mode of Action

Pentosan polysulfate sodium is a heparinoid with anticoagulant and fibrinolytic properties; it may also have hypolipidaemic and anti-inflammatory effects. It is used in thromboembolic disorders, although its anticoagulant effect is less than that of heparin. It is also used in the management of interstitial cystitis and has been tried in a number of other conditions, including variant Creutzfeldt-Jakob disease.

Interaction

Increased risk of bleeding when used with oral anticoagulants or drugs that affect platelet function. Concurrent admin with glyceryl trinitrate via IV route may reduce the efficacy of pentosan.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration

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