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GENTICIN 40mg/ml Price

Active Substance: Gentamicin (as sulfate).

179
UAD , based on 7541 reviews.
View Drug details

Overview

Welcome to Dwaey, specifically on GENTICIN 40mg/ml Injection page.
This medicine contains an important and useful components, as it consists of Gentamicin (as sulfate).
GENTICIN 40mg/ml is available in the market in concentration 40mg/ml and in the form of Injection.

NICHOLAS LAB. is the producer of GENTICIN 40mg/ml and it is imported from UK, The most popular alternatives of GENTICIN 40mg/ml are listed downward .

Mode Of Action

Gentamicin is an aminoglycoside that binds to 30s and 50s ribosomal subunits of susceptible bacteria disrupting protein synthesis, thus rendering the bacterial cell membrane defective.

Indication

  • Pneumonia
  • Cystic fibrosis
  • Meningitis
  • Peritonitis
  • Endocarditis
  • Susceptible infections
  • Septicaemia
  • Pelvic inflammatory disease
  • Endometritis
  • Biliary tract infections
  • Granuloma inguinale
  • Listeriosis
  • Gastroenteritis
  • Plague
  • Cat scratch disease
  • Brucellosis
  • Otitis externa
  • Surgical infections
  • Skin infections.

Precaution

History of hypersensitivity to aminoglycoside; pregnancy; hepatic impairment, perforated ear drum. Lactation: Enters breast milk; use with caution (AAP Committee states "compatible with nursing")

Side Effects

  • >10% Neurotoxicity (vertigo
  • ataxia)
  • Gait instability
  • Ototoxicity (auditory
  • vestibular)
  • Nephrotoxicity (decreased CrCl)
  • Nephrotoxicity if trough >2 mg/L 1-10% Edema
  • Rash
  • Reddening of skin
  • Itching <1% Drowsiness
  • Headache
  • Pseudomotor cerebri
  • Photosensitivity
  • Allergic reaction
  • Erythema
  • Anorexia
  • Nausea/vomiting
  • Weight loss
  • Increased salivation
  • Enterocolitis
  • Granulocytopenia
  • Agranulocytosis
  • Thrombocytopenia
  • Elevated LFT Burning
  • Stinging
  • Tremors
  • Muscle cramps
  • Weakness
  • Dyspnea Potentially Fatal: Nephrotoxicity
  • ototoxicity and neuromuscular blockade (may unmask or aggravate myasthaenia gravis).

Contra indication

History of hypersensitivity to aminoglycoside; pregnancy; hepatic impairment, perforated ear drum.

Pregnancy and lactation

Pregnancy category: D

There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Interaction

Synergistic with ampicillin, benzylpenicillin and other beta-lactam antibiotics. Increased risk of severe respiratory depression when used concurrently with anaesthetics or opioids. May reduce renal clearance of zalcitabine and induce hypocalcaemia when used with biphosphonates. Not to be used with agalsidase alfa or beta as it may inhibit alpha-galactosidase activity. Potentially Fatal: Increased incidence of ototoxicity when combined with ethacrynic acid and furosemide. Cephalosporins, ciclosporin, cisplatin, vancomycin, hydrocortisone and indometacin potentiate nephrotoxicity. Potentiates neuromuscular blocking agents.

Alternatives Price List

  • GENTICIN 40mg/mlUAD 36
  • GENTICIN 40mg/mlUAD 179
  • GENTICIN 10mg/ml (Paediatric)UAD 23
  • GENTACIN 0.3%UAD 9
  • GENTACIN 0.3%UAD 9

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