GELOMYRTOL FORTE Price

Overview

Welcome to Dwaey, specifically on GELOMYRTOL FORTE page.
This medicine contains an important and useful components, as it consists of
Distillate of a mixture of rectified essential oils of eucalyptus, sweet orange, myrtle and lemonis available in the market in concentration

Name

Ioversol

Precaution

Before initiating treatment with **Ioversol**, it is essential for patients to consult their healthcare provider, especially if they have the following conditions: - **Allergies to Contrast Agents**: **Ioversol** is a **contrast agent** used in diagnostic imaging, and some individuals may experience allergic reactions to iodine-based contrast materials. Patients with a history of **hypersensitivity** to contrast agents, iodine, or shellfish may be at increased risk of an allergic reaction. - **Kidney Disease**: **Ioversol** is primarily excreted by the kidneys, and in patients with **renal impairment**, there is an increased risk of developing **contrast-induced nephropathy** (CIN). Kidney function should be assessed before and after the administration of the contrast agent, especially in individuals with pre-existing kidney disease. - **Heart Disease**: Individuals with severe cardiovascular disease may be at an elevated risk of adverse reactions, especially if the contrast is administered intravenously, which can affect circulation. It is important to monitor for potential changes in **blood pressure** and **heart rate**. - **Thyroid Conditions**: Ioversol, like other iodine-based contrast agents, can affect **thyroid function**. Patients with **thyroid disorders**, especially those with **hyperthyroidism** or **iodine sensitivity**, should be closely monitored after receiving the agent. - **Pregnancy and Breastfeeding**: The use of **Ioversol** during pregnancy should be approached with caution. It should only be used when the potential benefits outweigh the risks, particularly during the first trimester. It is not known if **Ioversol** is excreted in breast milk, so breastfeeding mothers should consult their doctor to determine if they need to temporarily stop breastfeeding after the procedure.

Indication

**Ioversol** is primarily indicated for **diagnostic imaging** to enhance the quality of radiographic and CT scans. The drug helps to improve the visibility of certain areas within the body during imaging procedures. Its uses include: - **Computed Tomography (CT) Scanning**: It is commonly used for **CT scans** of the head, chest, abdomen, pelvis, and other areas. **Ioversol** helps to highlight blood vessels and organs to ensure clear imaging of tissues and structures. - **Angiography**: Ioversol is used in **angiographic procedures** to visualize blood vessels and to help diagnose vascular diseases and abnormalities, such as **blockages**, **aneurysms**, or **vascular malformations**. - **Excretory Urography**: For patients undergoing **urography** (a type of X-ray examination of the urinary tract), **Ioversol** assists in visualizing the kidneys, ureters, and bladder. - **Selective Arteriography**: It is used in the visualization of specific arteries during diagnostic exams to detect **vascular pathologies**.

Contra indication

**Ioversol** should not be used in the following circumstances: - **Hypersensitivity to Ioversol or Iodine**: **Ioversol** is contraindicated in patients with a known **allergy** or **hypersensitivity** to **iodine** or any components of the contrast agent. - **Severe Renal Impairment**: In patients with **severe renal dysfunction** or those who are at risk of developing **contrast-induced nephropathy**, use of Ioversol should be avoided or given with extreme caution. - **Hyperthyroidism**: Patients with **hyperthyroidism** or thyroid disorders should avoid using this contrast agent, as it can worsen thyroid conditions due to iodine exposure. - **Dehydration**: Patients who are **severely dehydrated** or have a history of fluid imbalance should not use **Ioversol**, as it may increase the risk of kidney complications. - **Severe Cardiovascular Disease**: It is contraindicated in patients with **severe cardiovascular conditions** where contrast use could exacerbate heart problems or cause adverse circulatory reactions.

Side Effect

While **Ioversol** is generally well-tolerated, it may cause side effects, which can range from mild to severe: - **Common Side Effects**: - **Injection Site Reactions**: Pain, redness, or swelling at the injection site may occur after intravenous administration of **Ioversol**. - **Warm Sensation**: Some patients may experience a **feeling of warmth** or **flushing** during or immediately after the injection. - **Nausea**: Mild **nausea** can occur, particularly during or following imaging procedures. - **Headache**: **Headaches** are reported occasionally as a side effect, especially during or after a diagnostic imaging procedure involving contrast. - **Serious Side Effects**: - **Contrast-Induced Nephropathy (CIN)**: One of the most serious side effects is **kidney damage**, especially in individuals with pre-existing kidney disease. This can manifest as **elevated serum creatinine** or **reduced urine output**. Renal function should be closely monitored following Ioversol administration. - **Allergic Reactions**: Severe allergic reactions, including **anaphylaxis**, are rare but possible. Symptoms may include **difficulty breathing**, **swelling**, **rash**, or **hives**. Immediate medical attention is required. - **Thyroid Dysfunction**: Given the iodine content in **Ioversol**, some patients may experience changes in thyroid function, including **hyperthyroidism** or **hypothyroidism**. - **Severe Hypotension**: In some cases, **hypotension (low blood pressure)** can occur, particularly in patients with cardiovascular issues.

Pregnancy Category ID

2

Mode of Action

**Ioversol** is an **iodine-containing contrast agent** used in diagnostic imaging. Its mechanism of action is based on its ability to absorb **X-rays**. This allows the contrast agent to create differences in **radiographic density** between different body structures, facilitating the visualization of internal organs and blood vessels during imaging procedures such as **CT scans** or **angiography**. - **X-ray Absorption**: The iodine atoms in **Ioversol** absorb X-rays more effectively than soft tissue, creating contrast between various tissues, making them more visible on the X-ray film or CT scan. - **Increased Visibility**: It increases the visibility of blood vessels, organs, and abnormalities, such as **tumors**, **plaques**, or **lesions**, enabling accurate diagnostic imaging.

Interaction

**Ioversol** may interact with other medications or substances, including: - **Renal-Function-Impacting Drugs**: Medications that affect kidney function, such as **NSAIDs**, **ACE inhibitors**, or **diuretics**, can increase the risk of kidney damage when used in conjunction with contrast agents like Ioversol. Special care should be taken in these patients, and renal function should be closely monitored before and after contrast administration. - **Metformin**: In patients receiving **metformin** for **diabetes**, there is a risk of **lactic acidosis** when contrast agents like Ioversol are used. It is recommended to temporarily discontinue **metformin** before contrast procedures and to resume it only once kidney function is confirmed to be normal. - **Antihypertensives**: Certain antihypertensive medications may interact with the contrast agent, altering blood pressure regulation, especially when given intravenously. Monitoring of blood pressure is essential. - **Thyroid Medications**: Due to the iodine content in **Ioversol**, there may be an interaction with thyroid medications. Thyroid function should be closely monitored in patients receiving the contrast agent, especially those on thyroid hormone replacement therapy.

Pregnancy Category Note

Information not available

Adult Dose

The dosing of **Ioversol** depends on the type of procedure being performed and the patient's body size. **Dosage recommendations** typically range as follows: - **For CT scans**: The usual dose for **CT imaging** ranges between **50-150 mL** (depending on the procedure), injected intravenously. For optimal imaging, the contrast agent is usually administered **slowly** to allow time for proper distribution. - **For Angiography**: In **angiographic procedures**, the dose can range from **20-80 mL**, depending on the size and type of the area being examined. - **Excretory Urography**: For **urography**, the usual dose is **50-100 mL**, given intravenously. Specific dosage will vary based on the patient's age, weight, medical condition, and the nature of the diagnostic imaging procedure. The healthcare provider will determine the precise amount needed based on the clinical situation.

Child Dose

The dosing for children depends on the procedure and the child’s weight: - **General Guidelines**: In pediatric patients, the dose is typically calculated based on weight, with doses typically ranging from **0.5 to 2.0 mL/kg** of body weight, depending on the specific type of diagnostic imaging procedure. - **Renal and Liver Monitoring**: As with adult patients, children with pre-existing kidney or liver conditions may require adjusted doses, and **renal function** should be closely monitored. As with adults, the pediatric dose will be determined by the healthcare provider based on the specific diagnostic requirements and the child's condition.

Renal Dose

In patients with **renal impairment**, dosing adjustments are crucial: - **Mild Renal Impairment**: In patients with mild kidney dysfunction, no significant dose reduction is typically necessary. However, kidney function should be monitored before and after the procedure. - **Moderate to Severe Renal Impairment**: In patients with moderate to severe renal impairment, careful consideration should be given before administering **Ioversol**, and **hydration** should be optimized to reduce the risk of contrast-induced nephropathy. Lower doses may be required.

Administration

Information not available