GAVISCON PEPPERMINT 250mg Price

Overview

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This medicine contains an important and useful components, as it consists of
Sodium alginate, Sodium hydrogen carbonate, Calcium carbonateis available in the market in concentration

Name

Iron + Folic Acid + Vitamin B + Vitamin C

Precaution

The combination of iron, folic acid, vitamin B, and vitamin C is often used to treat and prevent iron deficiency anemia and support overall health, particularly in individuals with nutritional deficiencies. However, there are several important precautions to consider. First, iron supplements can cause gastrointestinal side effects such as constipation, nausea, diarrhea, and abdominal discomfort. These side effects can be minimized by taking the supplement with food, although iron absorption is optimized when taken on an empty stomach. Vitamin C, which enhances iron absorption, may exacerbate gastrointestinal discomfort in sensitive individuals. Therefore, the combination should be used cautiously in people with a history of gastrointestinal issues like ulcers or irritable bowel syndrome (IBS). Vitamin B (especially B12 and B6) should be used with care in patients with neuropathy, as excessive intake may worsen symptoms in rare cases. Additionally, excessive folate intake (over 1000 mcg/day) can mask vitamin B12 deficiency, delaying diagnosis and treatment, which may lead to neurological damage. Pregnant women often use this combination to meet their increased nutritional needs, but dosage must be carefully controlled. An overdose of iron, particularly in children, can be fatal, so it is critical to store the supplement in a safe place. Blood tests should be done regularly to monitor iron, folate, and vitamin B levels, ensuring the body is receiving the correct amounts.

Indication

The combination of iron, folic acid, vitamin B (typically including B12 and B6), and vitamin C is primarily used to treat and prevent iron deficiency anemia, especially when there is a deficiency in one or more of these nutrients. Iron is crucial for the production of hemoglobin in red blood cells, while folic acid supports DNA synthesis and red blood cell production. Vitamin B12 and B6 are essential for energy metabolism and nerve function. Vitamin C enhances the absorption of iron, improving its bioavailability, especially when taken together. This combination is often prescribed for pregnant women, as both iron and folate requirements increase during pregnancy to support the growing fetus and prevent anemia. It is also used in individuals with poor dietary intake or conditions that impair nutrient absorption, such as gastrointestinal diseases. Additionally, this combination is helpful in treating anemia related to chronic blood loss (e.g., heavy menstruation or gastrointestinal bleeding) or recovering from surgeries or trauma. Off-label, it may be used in patients with chronic fatigue, nerve issues, or those undergoing treatments like chemotherapy that deplete the body of essential vitamins and minerals.

Contra indication

This combination of iron, folic acid, vitamin B, and vitamin C is contraindicated in individuals with iron overload disorders such as hemochromatosis, where excess iron accumulates in tissues and organs, leading to potential damage. In patients with a known allergy to any of the components (iron, folic acid, vitamin B, or vitamin C), the supplement should be avoided. Folic acid should be used cautiously in individuals with vitamin B12 deficiency because it can mask the symptoms of B12 deficiency, delaying diagnosis and potentially leading to irreversible neurological damage. The combination should also be avoided in individuals with active peptic ulcers, gastrointestinal bleeding, or other gastrointestinal disorders (such as Crohn’s disease or ulcerative colitis) as iron supplements can irritate the stomach and worsen symptoms. High doses of vitamin C (typically above 2,000 mg/day) can cause gastrointestinal upset, kidney stones, or other complications, so careful monitoring is necessary. Pregnant women should only use this combination under the guidance of a healthcare provider to ensure that the dosages of iron, folic acid, and vitamins B and C are appropriate. In children, iron overdose is particularly dangerous, so this supplement should be kept out of reach and should not be given unless prescribed by a healthcare provider.

Side Effect

The side effects of the combination of iron, folic acid, vitamin B, and vitamin C depend on the individual’s tolerance to each component. Common side effects include gastrointestinal issues such as constipation, nausea, diarrhea, abdominal pain, and bloating, particularly due to the iron content. These effects are often lessened when the supplement is taken with food, although iron absorption is better on an empty stomach. Iron supplements may also cause stool discoloration (dark or black stools), which is a harmless but common side effect. Folic acid, when taken in excessive amounts (above 1,000 mcg/day), can mask the symptoms of vitamin B12 deficiency, leading to potential neurological damage. Overconsumption of vitamin C can cause gastrointestinal disturbances, such as diarrhea, abdominal cramps, and nausea, and may contribute to the formation of kidney stones, particularly in those predisposed to them. Vitamin B6 at high doses (over 100 mg/day) can lead to nerve damage, resulting in symptoms like numbness or tingling. Rarely, allergic reactions such as skin rashes, itching, or swelling may occur. It is crucial to monitor for side effects and adjust the dosage accordingly. If any severe reactions or signs of overdose occur, medical attention should be sought immediately. Overdose of iron in children is particularly dangerous and can result in fatal poisoning, so it is critical to keep supplements out of their reach.

Pregnancy Category ID

0

Mode of Action

Iron, folic acid, vitamin B, and vitamin C work together to support the body's red blood cell production and overall metabolic processes. Iron is a key component of hemoglobin, the oxygen-carrying protein in red blood cells, and is necessary for the efficient transport of oxygen throughout the body. When iron levels are low, the production of hemoglobin decreases, leading to iron deficiency anemia. Folic acid (vitamin B9) is essential for DNA synthesis and red blood cell maturation. It works in conjunction with vitamin B12, which is required for folate metabolism and red blood cell development. Vitamin B6 also plays a role in the metabolism of amino acids and the production of neurotransmitters, supporting overall energy production and cellular function. Vitamin C enhances the absorption of non-heme iron (the type of iron found in plant-based foods and supplements), ensuring that iron is more efficiently utilized by the body. Vitamin C also acts as an antioxidant, protecting cells from oxidative stress and supporting immune function. The combined action of these nutrients improves red blood cell production, oxygen transport, and overall energy levels. By correcting deficiencies in iron, folate, and B vitamins, this combination helps alleviate the symptoms of anemia, such as fatigue, weakness, and shortness of breath, while also supporting overall metabolic health.

Interaction

Iron, folic acid, vitamin B, and vitamin C can interact with other medications and substances. For example, the absorption of iron can be reduced by antacids, proton pump inhibitors (PPIs), and certain antibiotics such as tetracyclines and fluoroquinolones. It is recommended to take iron supplements at least 2 hours apart from these medications. Iron absorption is enhanced by vitamin C, which is often included in the combination to improve iron bioavailability. However, excessive vitamin C (above 2,000 mg per day) can lead to gastrointestinal disturbances and increase the risk of kidney stones. The combination of folic acid and vitamin B12 should be monitored in individuals on long-term antiepileptic drugs (e.g., phenytoin, carbamazepine), as these drugs can interfere with the effectiveness of folate and B12. High doses of folic acid can mask a vitamin B12 deficiency, leading to neurological damage if not detected. Iron may also interact with levodopa (used to treat Parkinson’s disease), reducing its absorption. Certain foods, such as calcium-rich dairy products or coffee, may decrease iron absorption, so it is advised to avoid taking the supplement alongside such foods. Alcohol may increase the risk of gastrointestinal irritation and should be limited during supplementation.

Pregnancy Category Note

Information not available

Adult Dose

The typical adult dose for a combination of iron, folic acid, vitamin B, and vitamin C varies depending on the specific formulation, but a common dose involves 1 tablet per day, with each tablet containing 325 mg of ferrous sulfate (providing approximately 65 mg of elemental iron), 400 mcg of folic acid, 1–2 mg of vitamin B12, and 60 mg of vitamin C. The supplement is typically taken once daily, although the dosage may be adjusted based on individual needs and the severity of deficiencies. The iron supplement should ideally be taken on an empty stomach to maximize absorption, although it may be taken with food if gastrointestinal side effects occur. Treatment duration may vary but typically lasts for several months until iron and vitamin levels are normalized. For pregnant women, the dose may be increased to meet the higher iron and folate requirements, and the healthcare provider will tailor the dosage to the individual's specific needs. Iron supplementation should not exceed the recommended dose to avoid iron overload, and regular blood tests are advised to monitor iron and vitamin levels during treatment.

Child Dose

For children, the dose of iron, folic acid, vitamin B, and vitamin C should be determined based on the child’s age, weight, and nutritional needs. In general, for children aged 6 months to 2 years, a lower dose of 1/2 to 1 tablet per day is typically recommended, depending on the child's nutritional status and iron deficiency severity. Children aged 2 years and older may take 1 tablet per day, but this should be prescribed by a healthcare provider. It is essential to monitor for side effects, such as gastrointestinal discomfort or constipation, and adjust the dosage accordingly. Overdose of iron in children is dangerous and can result in life-threatening toxicity, so proper dosing and safe storage of supplements are crucial. Regular monitoring of iron, folate, and vitamin B levels during treatment is essential to ensure safe and effective supplementation.

Renal Dose

In patients with renal impairment, no specific dose adjustments for iron, folic acid, vitamin B, and vitamin C are generally required, as these nutrients are absorbed in the gastrointestinal tract and not excreted through the kidneys. However, in cases of severe kidney disease or end-stage renal disease (ESRD), iron supplementation should be closely monitored, as individuals with kidney disease are at higher risk for iron overload. Additionally, people with kidney dysfunction may require additional folate supplementation due to reduced renal clearance of folate. Regular monitoring of iron, folate, and vitamin B levels is important in these patients to avoid excessive accumulation. In patients with chronic kidney disease (CKD), adjustments may be needed based on laboratory results to ensure that appropriate amounts of each nutrient are provided.

Administration

Information not available