FORTEPEN 0.4MIU Price in UAE

Overview

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This medicine contains an important and useful components, as it consists of
Penicillin G sodium (Benzyl Penicillin Sodium), Procaine Benzyl Penicillinis available in the market in concentration

Name

Benzyl Penicillin + Procaine Penicillin

Precaution

Penicillin should be used with caution in individuals with histories of significant allergies and/or asthma. Care should be taken to avoid intravenous or intra-arterial administration, or injection into or near major peripheral nerves or blood vessels, since such injections may produce neurovascular damage Lactation: Excreted into breast milk, caution advised

Indication

Meningitis, Peritonitis, Anthrax, Non-gonococcal urethritis, Diphtheria, Syphilis, Infections caused by Staphylococcus (susceptible strains), Streptococcus, Pneumococcus species gonorrhoea, Subacute bacterial endocarditis, Upper respiratory tract, Erysipelas, Skin and soft tissue infections, Moderately severe pneumonia and otitis media, Empyema, Bacteremia, Pericarditis, Arthritis

Contra indication

A previous hypersensitivity reaction to any penicillin or to procaine is a contraindication.

Side Effect

As with other penicillins, untoward reactions of the sensitivity phenomena are likely to occur, particularly in individuals who have previously demonstrated hypersensitivity to penicillins or in those with a history of allergy, asthma, hay fever, or urticaria. The following have been reported with parenteral penicillin G: General: Hypersensitivity reactions including the following: skin eruptions (maculopapular to exfoliative dermatitis), urticaria, laryngeal edema, fever, eosinophilia; other serum sickness-like reactions (including chills, fever, edema, arthralgia, and prostration); and anaphylaxis including shock and death. Gastrointestinal: Pseudomembranous colitis. Onset of pseudomembranous colitis symptoms may occur during or after antibacterial treatment.

Pregnancy Category ID

2

Mode of Action

Benzylpenicillin has a bactericidal action against gram-positive bacteria, gram-negative cocci, some other gram-negative bacteria, spirochetes and actinomycetes. It inhibits final cross-linking stage of peptidoglycan production through binding and inactivation of transpeptidases on the inner surface of the bacterial cell membrane thus inhibiting bacterial cell wall synthesis. It is inhibited by penicillinase and other ?-lactamases. Interferes with cell wall mucopeptide synthesis during active multiplication, resulting in bactericidal activity against susceptible microorganisms.