Active Substance: Levonorgestrel.
Overview
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This medicine contains an important and useful components, as it consists of
Levonorgestrelis available in the market in concentration
Levonorgestrel
Sex-steroid dependent cancer, past ectopic pregnancy, malabsorption syndromes, functional ovarian cysts, active liver disease, recurrent cholestatic jaundice, history of jaundice in pregnancy, CV or renal impairment, DM, asthma, epilepsy, migraine, conditions aggravated by fluid retention, depression and thromboembolism (high doses); lactation.
Contraception , Emergency contraception , Menopausal hormone replacement therapy , Menorrhagia,
Pregnancy, undiagnosed vaginal bleeding, severe arterial disease; liver adenoma, porphyria; after recent evacuation of hydatidiform mole; history of breast cancer; hepatic impairment.
>10% Headache (12%),Acne (15%),Ovarian cysts (13%),Enlarged follicles (12%),Amenorrhea (1-12%),Abdominal pain (12%),Uterine/vaginal bleeding alterations (52%),Intermenstrual bleeding/spotting (23%),Vulvovaginitis (20%),Ectopic pregnancy (?50%) 1-10% Depression (4%),Migraine (2%),Alopecia (1%),Dysmenorrhea (9%),Menorrhagia (6%),Breast tenderness (3-9%),Pelvic pain (6%),Leukorrhea (5%),Vaginal discharge (4%),Pelvic infection (1%) <1% Angioedema,Cervical perforation,Failed insertion,Sepsis,Uterine bleeding,Device breakage Potentially Fatal: Thrombocytopenia, stroke.
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Levonorgestrel, a nortestosterone derivative, is an active isomer of norgestrel. It is a potent inhibitor of ovulation and has androgenic activity.
Reduced efficacy with enzyme-inducing drugs; aminoglutethimide. May inhibit ciclosporin metabolism.
Information not available