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ENHERTU 100mg Price

Active Substance: Trastuzumab Deruxtecan.

9165
UAD , based on 7541 reviews.
View Drug details

Overview

Welcome to Dwaey, specifically on ENHERTU 100mg Powder for concentrate for solution for Infusion page.
This medicine contains an important and useful components, as it consists of Trastuzumab Deruxtecan.
ENHERTU 100mg is available in the market in concentration 100 mg/Vial and in the form of Powder for concentrate for solution for Infusion.

ASTRAZENECA UK LTD. is the producer of ENHERTU 100mg and it is imported from UK, The most popular alternatives of ENHERTU 100mg are listed downward .

Mode Of Action

Trastuzumab, a monoclonal antibody, has action directed against a cell surface protein produced by human epidermal growth factor receptor 2 (HER2). It inhibits proliferation of tumour cells that overexpress HER2 e.g. in 1/3 of breast cancer.

Indication

  • Breast cancer
  • Gastric cancer

Precaution

Patient w/ pre-existing CV and pulmonary disease; extensive pulmonary tumour involvement. Pregnancy and lactation. Monitoring Parameters Monitor cardiac function prior and during treatment. Lactation: not known if excreted in breast milk, discontinue nursing during treatment and for 6 months after last dose

Side Effects

  • >10% Pain (47%)
  • Asthenia (42%)
  • Fever (36%)
  • Nausea (33%)
  • Chills (32%)
  • Cough (26%)
  • Headache (26%)
  • Diarrhea (25%)
  • Vomiting (23%)
  • Abdominal pain (22%)
  • Back pain (22%)
  • Dyspnea (22%)
  • Infection (20%)
  • Rash (18%)
  • Anorexia (14%)
  • Insomnia (14%)
  • Dizziness (13%) 1-10% Flu-like syndrome (10%)
  • Peripheral edema (10%)
  • CHF (7%)
  • Depression (6%)
  • Tachycardia (5%)
  • UTI (5%)
  • Anemia (4%)
  • Hypersensitivity (3%)
  • Leukopenia (3%) Potentially Fatal: Severe hypersensitivity (anaphylaxis) and infusion reactions; pulmonary events e.g. acute respiratory distress syndrome; cardiotoxicity. Neutropenia (especially when given with chemotherapy).

Contra indication

Lactation (start only 6 mth after last dose of drug). Do not admin by rapid IV or bolus inj.

Pregnancy and lactation

Pregnancy category: D

There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Interaction

Increased risk of severe cardiotoxicity with anthracyclines. Increased risk of leukopenia and anaemia in combination chemotherapy (e.g. paclitaxel). Paclitaxel may decrease the clearance of trastuzumab. Increased risk of bleeding with warfarin.

Alternatives Price List

  • ENHERTU 100mgUAD 9165

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