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EDARBI 40mg Price

Active Substance: Azilsartan medoxomil (as potassium).

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UAD , based on 7541 reviews.
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Overview

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This medicine contains an important and useful components, as it consists of
Azilsartan medoxomil (as potassium)is available in the market in concentration

Name

Azilsartan Medoxomil

Precaution

Correct vol or salt depletion prior to administration. Renal (moderate to severe) & hepatic (severe) impairment. Pregnancy (1st trimester) & lactation. Childn <18 yr. Monitor serum K in patients taking K-sparing diuretics, salt substitutes containing K & drugs that increase K levels (eg heparin) & creatinine levels in patients w/ renal impairment & type 2 DM. Aortic or mitral valve stenosis, hypertrophic obstructive cardiomyopathy. Lactation: unknown whether distributed in breast milk, decide on alternate antihypertensive therapy or do not breastfeed

Indication

Treatment of Hypertension, alone or in combination w/ other antihypertensive agents.

Contra indication

Hypersensitivity. Pregnancy.

Side Effect

1-10% Diarrhea (2%) <1% Nausea,Asthenia,Fatigue,Muscle spasm,Dizziness,Postural hypotension,Cough

Pregnancy Category ID

4

Mode of Action

Angiotensin II blocker; displaces angiotensin II from AT1 receptor and may lower blood pressure by antagonizing AT1-induced vasoconstriction, aldosterone release, catecholamine release, arginine vasopressin release, water absorption, and hypertrophic responses. May induce more complete inhibition of renin-angiotensin system compared with ACE inhibitors; does not affect response to bradykinin. Inhibits the pressor effects of an angiotensin II infusion in a dose-related manner.

Interaction

Reversibly increases serum conc & toxicity of lithium; attenuated antihypertensive effects & risk of worsening of renal function may occur w/ NSAIDs. Hyperkalemia w/ K-sparing diuretics & K supplements.

Pregnancy Category Note

Pregnancy Category: C (1st trimester); D (2nd and 3rd trimesters)

Adult Dose

Child Dose

Renal Dose

Administration

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