Active Substance: Betamethasone (as dipropionate), Gentamicin.
Overview
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This medicine contains an important and useful components, as it consists of
Betamethasone (as dipropionate), Gentamicinis available in the market in concentration
Betamethasone 0.05% + Gentamicin 0.1% E E prep
Prolonged ophthalmic usage may increase the intraocular pressure. Monitor intraocular pressure if treatment lasts for >10 days. Prolonged use of ophthalmic corticosteroid may increase the risk of cataract formation. Increases the risk of perforation in diseases causing thinning of the cornea or sclera. Use of topical corticosteroids may lead to reactivation of disease in patients with a history of herpetic infection of the cornea. Steroid use after cataract surgery may increase risk of filtering blebs and delay healing. Prolonged use may also suppress immune response and increase risk of secondary infections. Pregnancy and lactation.
Ocular and ear inflammation with bacterial infection
Hypersensitivity. Ophthalmic preparations should not be used in epithelial herpes simplex keratitis (dendritic keratitis), varicella, and many other viral diseases of the cornea and conjunctiva, mycobacterial infections of the eye, trachoma, fungal diseases of ocular structures. Not to be used after removal of a corneal foreign body or in the presence of acute local viral lesions e.g. herpes, and in patients with absent or perforated tympanic membranes.
Ophthalmic: Increased ocular pressure, increased ocular hyperemia, oedema and burning sensation. May also cause anterior uveitis or perforation of the globe. Otic: May cause ototoxicity.
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Betamethasone is a corticosteroid that has anti-inflammatory activity. Gentamicin is an aminoglycoside that has broad spectrum bactericidal activity; it is active against a wide variety of pathogenic gram-negative and gram-positive bacteria.
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