CAMCOLIT 400mg Price

Overview

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This medicine contains an important and useful components, as it consists of
Lithium carbonateis available in the market in concentration

Name

Lithium Carbonate

Precaution

Decreased tolerance to lithium has been reported to ensue from protracted sweating or diarrhoea and, if such occur, supplemental fluid and salt should be administered under careful medical supervision and lithium intake reduced or suspended until the condition is resolved. Lactation: Drug is excreted in breast milk; use not recommended

Indication

Bipolar disorder, Mania, Recurrent unipolar depression

Contra indication

Renal insufficiency, cardiovascular insufficiency, Addisons disease and untreated hypothyroidism are all contraindications to lithium therapy.

Side Effect

>10% Leukocytosis (most patients),Polyuria/polydypsia (30-50%),Dry mouth (20-50%),Hand tremor (45% initially, 10% after 1 year of treatment),Confusion (40%),Decreased memory (40%),Headache (40%),Muscle weakness (30% initially, 1% after 1 year of treatment),Electrocardiographic (ECG) changes (20-30%),Nausea, vomiting, diarrhea (10-30% initially, 1-10% after 1-2 years of treatment),Hyperreflexia (15%),Muscle twitch (15%),Vertigo (15%) 1-10% Extrapyramidal symptoms, goiter (5%),Hypothyroidism (1-4%),Acne (1%),Hair thinning (1%) Frequency Not Defined Coma,Lethargy,Seizures,Renal toxicity

Pregnancy Category ID

4

Mode of Action

Inhibits postsynaptic D2 receptor supersensitivity. Alters cation transport in nerve and muscle cells and influences reuptake of serotonin or norepinephrine. Inhibits phosphatidylinositol cycle second messenger systems.

Interaction

Reduced serum levels with carbonic anhydrase inhibitors, chlorpromazine, sodium-containing preparations, theophylline, urea. Enhanced hypothyroid effects with iodine salts. Enhanced effects of neuromuscular-blocking agents. Reduced pressor response to sympathomimetics. Potentially Fatal: Increased risk of lithium toxicity with ACE inhibitors, angiotensin receptor antagonists, loop diuretics, metronidazole, phenytoin. Increased risk of neurotoxicity with carbamazepine, calcium-channel blockers, haloperidol, methyldopa, phenothiazines, SSRIs, TCAs. Increased serum levels with COX-2 inhibitors, NSAIDs (except sulindac, aspirin), tetracyclines, thiazide diuretics. Increased risk of encephalopathy with haloperidol. Increased risk of serotonin syndrome with sibutramine. Fatal malignant hyperpyrexia may occur when used with MAOIs.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration