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DETRUSITOL 2mg

Active Substance: Tolterodine l-tartrate.

175
UAD , based on 7541 reviews.
View Drug details
Overview

Welcome to Dwaey, specifically on DETRUSITOL 2mg Tablets page.
This medicine contains an important and useful components, as it consists of Tolterodine l-tartrate.
DETRUSITOL 2mg is available in the market in concentration 2mg/Tablet and in the form of Tablets.

PFIZER ITALIANA S.p.A. is the producer of DETRUSITOL 2mg and it is imported from ITALY, The most popular alternatives of DETRUSITOL 2mg are listed downward .

Mode Of Action & Indication

Tolterodine is a competitive muscarinic receptor antagonist with actions similar to atropine. It is used in the management of urge urinary incontinence, urgency and frequency.

Indication
  • Overactive bladder
Precaution

Bladder flow obstruction, GI obstructive disorders, renal or hepatic impairment, autonomic neuropathy, hiatus hernia, risk of decreased GI motility, patients at risk of QT interval prolongation (e.g. electrolyte disturbances, bradycardia, pre-exisiting cardiac disorder). Lactation: Unknown whether drug is distributed in breast milk; do not nurse

Side Effects
  • >10% Dry mouth (40%) 1-10% Blurred vision
  • Constipation
  • Dizziness
  • Drowsiness
  • Dyspepsia
  • Headache
  • Xerophthalmia
Alternatives Price List
  • DETRUSITOL RETARD 4mgUAD 103
  • DETRUSITOL RETARD 2mgUAD 103
  • DETRUSITOL 2mgUAD 78
  • DETRUSITOL 2mgUAD 175
  • DETRUSITOL 1mgUAD 160
Contra indication

Severe ulcerative colitis, toxic megacolon, urinary retention, gastric retention, myasthenia gravis, uncontrolled narrow-angle glaucoma, pregnancy.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Increased risk of overdosage with potent CYP3A4 inhibitors e.g. macrolide antibiotics (erythromycin and clarithromycin), azole antifungals (e.g. ketoconazole and itraconazole), protease inhibitors, ciclosporin or vinblastine. Increased risk of torsade de pointes with drugs that prolong the QT interval (e.g. class Ia and class III antiarrhythmics). Increased risk of 'cholinergic neurogenic hypersensitivity' with centrally acting anticholinesterases (e.g. donepezil, rivastigmine). Increased risk of antimuscarinic side effects with antimuscarinic drugs.

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