BURINEX 1mg price in UAE

Overview

Welcome to Dwaey, specifically on BURINEX 1mg Tablets page.
This medicine contains an important and useful components, as it consists of Bumetanide.
BURINEX 1mg is available in the market in concentration 1mg/Tablet and in the form of Tablets.

LEO PHARMACEUTICAL CO. is the producer of BURINEX 1mg and it is imported from DENMARK, The most popular alternatives of BURINEX 1mg are listed downward .

Mode Of Action

Bumetanide induces diuresis by inhibiting reabsorption of water and electrolytes (sodium and chloride) in the ascending loop of Henle and proximal renal tubule.

Indication

Hypertension
Heart failure
Oedema
Nephrotic syndrome

Precaution

Pregnancy, lactation; regular monitoring of serum electrolytes (especially potassium, calcium, magnesium); in case of hypokalemia, potassium supplements/potassium-sparing diuretics added. Monitor blood-glucose, BUN, creatinine levels as well as blood counts. Sulfonamide allergy. CHF patients on digitalis, K losing nephropathy, hepatic cirrhosis and ascitis, diarrhoeal states. Lactation: Unknown whether drug is excreted in breast milk; use with caution

Side Effects

>10% Hyperuricemia (18%)
Hypochloremia (15%)
Hypokalemia (15%)
Azotemia (11%) 1-10% Hyponatremia (9%)
Hyperglycemia (7%)
Increased serum creatinine (7%)
Variations in phosphorus (5%)
Variations in CO2 content (4%)
Variations in bicarbonate (3%)
Variations in calcium (2%)
Dizziness (1%)
Muscle cramps (1%)
Ototoxicity (1%) <1% Asterixis
Dehydration
Hypotension
Orthostatic hypotension
Pruritus
Rash
Renal failure
Serious skin reactions (ie
Stevens-Johnson syndrome
toxic epidermal necrolysis)
Vertigo
Vomiting Potentially Fatal: Encephalopathy (in patients with preexisting liver disease).

Contra indication

Hypersensitivity, progressive renal failure and anuria, hepatic coma, severe electrolyte depletion.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Reduced diuretic and natriuretic actions by probenecid. Indometacin blunts action of bumetanide; concurrent usage with antihypertensives may increase risk of orthostatic hypotension. Potentially Fatal: Avoid concurrent usage with ototoxic drugs such as aminoglycoides and nephrotoxic drugs. Reduced lithium excretion via kidneys.