Active Substance: Cefdinir.
Overview
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This medicine contains an important and useful components, as it consists of
Cefdiniris available in the market in concentration
Cefdinir
Penicillin-sensitive patients; superinfection; seizure; pseudomembranous colitis; pregnancy, lactation; renal or hepatic insufficiency. Lactation: Unknown whether drug is excreted in milk
Community-acquired pneumonia, Susceptible infections, Sinusitis, Otitis media, Sore throat, Soft tissue infections, Respiratory tract infections, Acute Exacerbations of Chronic bronchitis, Acute Maxillary Sinusitis
Hypersensitivity.
>10% Diarrhea (8-15%) 1-10% Vaginal moniliasis (<4%),Nausea (3%),Rash (3%),Headache (2%),Increased urine leukocytes (2%),Increased urine protein (1-2%),Decreased lymphocytes (1%),Glycosuria (1%),Increased alkaline phosphatase (1%),Increased eosinophils (1%),Increased platelets (1%) Potentially Fatal: Anaphylaxis; renal and hepatic failure.
2
Cefdinir binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.
Concomitant admin w/ antacids or Fe supplements reduce the rate and extent of absorption. Admin w/ Fe supplements may cause reddish stools. Decreased renal elimination w/ probenecid.
Information not available