Overview

Welcome to Dwaey, specifically on DEPULOX 60 Capsules (Hard Gelatin) page.
This medicine contains an important and useful components, as it consists of Duloxetin HCl.
DEPULOX 60 is available in the market in concentration 60mg/Capsule and in the form of Capsules (Hard Gelatin).

NEXGEN PHARMA FZ LLC is the producer of DEPULOX 60 and it is imported from UAE, The most popular alternatives of DEPULOX 60 are listed downward .

Mode Of Action & Indication

Duloxetine is a potent inhibitor of neuronal reuptake of serotonin, norepinephrine and to a lesser extent dopamine. It has no significant affinity for adrenergic, muscarinic, cholinergic, histaminergic, opioid, glutamate and GABA receptors. It also does not inhibit monoamine oxidase.

Indication

• Major Depressive Disorder (MDD)
• Fibromyalgia
• Diabetic neuropathy
• Stress urinary incontinence
• Generalized anxiety disorder
• Interstitial cystitis
• Musculoskeletal pain

Precaution

Avoid alcohol and abrupt cessation. May impair ability to drive or engage in task requiring alertness. Increased risk of suicidal thinking and behaviour when used in children and adolescents. Pregnancy, lactation. Lactation: Drug enters breast milk; use not recommended unless benefits greatly outweigh risks

Side Effects

• >10% Nausea (23-25%)
• Dry mouth (13-15%)
• Headache (13-14%)
• Somnolence (10-12%)
• Fatigue (10-11%) 1-10% Constipation (10%)
• Dizziness (10%)
• Insomnia (10%)
• Diarrhea (9-10%)
• Anorexia (8%)
• Decreased appetite (7-8%)
• Abdominal pain (6%)
• Hyperhidrosis (6%)
• Increased sweating (6%)
• Agitation (5%)
• Nasopharyngitis (5%)
• Vomiting (3-5%)
• Male sexual dysfunction (2-5%)
• Abdominal pain (4%)
• Decreased libido (4%)
• Musculoskeletal pain (4%)
• Upper respiratory tract infection (URTI) (4%)
• Abnormal orgasm (3%)
• Agitation (3%)
• Anxiety (3%)
• Blurred vision (3%)
• Cough (3%)
• Influenza (3%)
• Muscle spasms (3%)
• Tremor (3%)
• Abnormal dreams (2%)
• Dyspepsia (2%)
• Hot flushes (2%)
• Nausea (2%)
• Oropharyngeal pain (2%)
• Palpitations (2%)
• Paresthesia (2%)
• Weight loss (2%)
• Yawning (2%)
• Dysuria (>1%)
• Gastritis (>1%)
• Rash (>1%)

Contra indication

Duloxetine is contraindicated in patients with a known hypersensitivity to this drug or any of the inactive ingredients.. Uncontrolled narrow-angle glaucoma. Concomitant use or within 2 wk of MAOIs. Renal and hepatic impairment.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks