AVONEX 30mcg/0.5ml Price

Overview

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This medicine contains an important and useful components, as it consists of
Interferon beta-1ais available in the market in concentration

Name

Interferon Beta 1a

Precaution

Caution when used in patients with depression or psychiatric disorders, epilepsy or other CNS diseases, poorly controlled thyroid dysfunction, pulmonary disease, DM, renal or hepatic impairment, cardiac disorders, myelosuppression, auto-immune diseases, coagulation disorders, or a history of these conditions. Monitor blood counts especially in patients at high risk of myelosuppression. Eye examination should be conducted prior to starting treatment and regularly thereafter. Monitor hepatic and renal function regularly. Treatment should be discontinued in patients with chronic hepatitis who develop liver decompensation. May affect ability to drive or operate machinery. Pregnancy. Lactation: unknown; use caution

Indication

Multiple Sclerosis

Contra indication

Hypersensitivity to beta interferons, albumin (for albumin-containing formulations)

Side Effect

>10% Injection site reactions (83% [SC]; 28% [IM],Headache (67%),Flu-like syndrome (61%),Muscle ache (34%),Nausea (33%),URT infection (14%),Pain (24%),Fever (23%),Asthenia (21%),Diarrhea (16%),Dizziness (15%),Infection (11%),Dyspepsia (11%) 1-10% Abdominal pain (9%),Anemia (8%),Chest pain (6%) <1% Aggravation of seizure disorders

Pregnancy Category ID

3

Mode of Action

Interferon beta 1a alters the expression and response to surface antigens and can improve immune cell activities. It has antiviral and immunomodulating properties.

Interaction

May increase the adverse effects (especially granulocytopenia) of ACE inhibitors. Increased risk of hepatic injury when used with hepatotoxic drugs. May increase serum levels of theophylline derivatives. May increase the anticoagulant effects of warfarin. May decrease the metabolism of zidovudine.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration