Overview

Welcome to Dwaey, specifically on DEPO MEDROL 40mg/ml Injection page.
This medicine contains an important and useful components, as it consists of Methylprednisolone acetate.
DEPO MEDROL 40mg/ml is available in the market in concentration 40mg/ml and in the form of Injection.

PFIZER S.A. is the producer of DEPO MEDROL 40mg/ml and it is imported from BELGIUM, The most popular alternatives of DEPO MEDROL 40mg/ml are listed downward .

Mode Of Action & Indication

Methylprednisolone is a synthetic corticosteroid with mainly glucocorticoid activity and minimal mineralocorticoid properties. It decreases inflammation by suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability.

Indication

• Anti-inflammatory or immunosuppressive
• Allergic conditions

Precaution

Patient w/ heart failure, HTN, DM, GI disease (e.g. diverticulitis, intestinal anastomoses, peptic ulcer, ulcerative colitis), multiple sclerosis, myasthenia gravis, acute MI, cataracts, glaucoma, osteoporosis, history of seizure disorder, thyroid disease. Avoid abrupt withdrawal. Renal and hepatic impairment (including cirrhosis). Childn. Pregnancy and lactation. Monitoring Parameters Monitor BP, blood glucose, electrolytes, growth in childn. Lactation: Drug enters milk; use with caution

Side Effects

• Adrenal suppression
• anaphylactoid reactions
• immunosuppression
• acute myopathy
• Kaposi's sarcoma
• psychiatric disturbances (e.g. depression
• euphoria
• insomnia
• mood swings
• personality changes)
• increased susceptibility and severity of infections
• impaired healing
• HTN
• Na and fluid retention
• CV collapse (high dose)
• peptic ulcer
• cataract subcapsular
• skin atrophy
• acne
• muscular weakness
• growth retardation
• decreased blood K; dermal/subdermal skin depression at inj site. Topical: Itching
• burning erythema
• vesiculation; rarely
• folliculitis
• hypertrichosis
• perioral dermatitis
• skin discolouration
• allergic skin reactions.

Contra indication

Systemic fungal infections and known hypersensitivity to components.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks