Active Substance: Sodium hyaluronate 2.400mg.
Overview
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This medicine contains an important and useful components, as it consists of
Sodium hyaluronate 2.400mgis available in the market in concentration
Sodium Hyaluronate
Use caution when injecting Sodium Hyaluronate into patients who are allergic to avian proteins, feathers, and egg products. Strict aseptic administration technique must be followed. Remove joint effusion, if present, before injecting Sodium Hyaluronate. Do not use the same syringe for removing joint effusion and for injecting Sodium Hyaluronate. It is recommended that the patient avoid any strenuous activities or prolonged (i.e., more than 1 hour) weight-bearing activities such as jogging or tennis within 48 hours following the intra-articular injection.
Osteoarthritis
Hypersensitivity to sodium hyaluronate or avian proteins. Intra-articular injections are contraindicated in cases of past and present infections or skin diseases in the area of the injection site.
Intra-articular inj: Pain and inflammation at inj site. Hypersensitivity; anaphylaxis; hypotensive crisis. The common side-effects include gastrointestinal complaints, knee swelling/effusion, local skin reactions (rash, ecchymosis), pruritus, and headache.
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Sodium hyaluronate is a polysaccharide which functions as a tissue lubricant. It is widely used in ophthalmic surgery because it forms a viscoelastic solution in water which makes it a suitable substitute for aqueous and vitreous humour.
The safety and effectiveness of the use of sodium hyaluronate concomitantly with other intra-articular injection has not yet been established. As sodium hyaluronate is precipitated by quaternary amine bactericides or disinfectants eg, benzalkonium chloride and chlorhexidine, etc, adequate attention should be given.
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