Overview

Welcome to Dwaey, specifically on ZOMIG 2.5mg Tablets/Coated page.
This medicine contains an important and useful components, as it consists of Zolmitriptan.
ZOMIG 2.5mg is available in the market in concentration 2.5mg/Tablet and in the form of Tablets/Coated.

ASTRAZENECA D.O.O is the producer of ZOMIG 2.5mg and it is imported from CROATIA, The most popular alternatives of ZOMIG 2.5mg are listed downward .

Mode Of Action & Indication

Zolmitriptan is a selective agonist for serotonin (5HT1 receptors). It relieves migraine by selective constriction of intracranial blood vessels, neuropeptide release inhibition and decreased transmission in the trigeminal pain pathway.

Indication

• Acute migraine attacks

Precaution

Use only if there is a clear diagnosis of migraine; exclude other potentially serious neurological conditions. Monitor BP closely. May impair ability to drive or operate machinery. Pregnancy and lactation. Child. Moderate to severe hepatic impairment. Prior CV evaluation for patients with risk factors of coronary heart disease; admin of first dose under close supervision and ECG if satisfactory CV assessment in these patients. Periodic CV evaluation for patients with risk factors of coronary arteries on zolmitriptan. Avoid oral disintegrating formulation for patients with phenylketouria. Long term use may cause accumulation of zolmitriptan in melanin rich tissue (e.g. eye). Lactation: unknown, use caution

Side Effects

• 1-10% Dizziness (6-10%)
• Neck/throat/jaw pain (4-10%)
• Parasthesia (5-9%)
• Nausea (4-9%)
• Weakness (3-9%)
• Somnolence (5-8%)
• Warm/cold sensation (5-7%)
• Xerostomia (3-5%)
• Chest pain (2-4%)
• Diaphoresis (3%)
• Pain (2-3%)
• Dyspepsia (1-3%)
• Dysphagia (2%)
• Myasthenia (2%)
• Palpation (2%)
• Vertigo (2%)
• Hypoesthesia (1-2%)
• Myalgia (1-2%) <1% QT prolongation
• Bradycardia
• Tachycardia
• Thrombophlebitis
• Postural hypotension
• Hyperglycemia
• Alk phos increased
• Arthritis
• Twitching
• Myocardial infarction and artery vasospasm in patients with CAD risk factors Potentially Fatal: Cardiac arrhythmias
• MI
• subarachnoid haemorrhage.

Contra indication

Patients at risk of coronary artery disease (post-menopausal women, men >40 yr, hypertension, hypercholesterolemia, smoking, obesity, DM, family history of coronary artery disease) unless evaluated. Wolff-Parkinson-White syndrome; arrhythmias associated with accessory cardiac conduction pathways; previous cerebrovascular accident; uncontrolled or severe hypertension; ischaemic heart disease, history of MI, coronary vasospasm, transient ischaemic attack. Basilar or hemiplegic migraine.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks