ZINNAT 500mg Price

Overview

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This medicine contains an important and useful components, as it consists of Cefuroxime (as axetil).
ZINNAT 500mg is available in the market in concentration 500mg/Tablet and in the form of Tablets.

GLAXO OPERATIONS UK LTD. is the producer of ZINNAT 500mg and it is imported from UK, The most popular alternatives of ZINNAT 500mg are listed downward .

Mode Of Action

Cefuroxime binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.

Indication

• Pharyngitis
• Acute otitis media
• Lyme disease
• Susceptible infections
• Sinusitis
• Otitis media
• Skin and skin structure infections
• Tonsillitis
• Respiratory tract infections
• Acute Maxillary Sinusitis
• Urinary tract infections
• Acute bacterial exacerbation of chronic bronchitis
• Surgical Prophylaxis

Precaution

Severe renal impairment; pregnancy, lactation; hypersensitivity to penicillins. Lactation: Drug excreted in breast milk; use with caution

Side Effects

• >10% Diarrhea (4-11%; depends on duration) 1-10% Decreased hemoglobin or hematocrit (10%)
• Eosinophilia (7%)
• Nausea or vomiting (3-7%)
• Vaginitis (<5%)
• Transient rise in hepatic transaminases (2-4%)
• Diaper rash (3%)
• Increase in alkaline phosphatase (2%)
• Thrombophlebitis (2%)
• Increase in lactate dehydrogenase (1%) <1% Anemia
• Cholestasis
• Colitis
• Dyspnea
• Epidermal necrolysis
• Increase in blood urea nitrogen (BUN) and creatinine
• Jaundice
• Nephritis
• Prolonged prothrombin time (PT)/international normalized ratio (INR)
• Rash
• Stevens-Johnson syndrome
• Stomach cramps
• Transient neutropenia and leukopenia
• Urticaria Potentially Fatal: Anaphylaxis
• nephrotoxicity
• pseudomembranous colitis.

Contra indication

Hypersensitivity to cephalosporins.

Pregnancy and lactation

Pregnancy category: B

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.