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ZINNAT 125mg Price

Active Substance: Cefuroxime (as axetil).

28
UAD , based on 7541 reviews.
View Drug details

Overview

Welcome to Dwaey, specifically on ZINNAT 125mg Tablets page.
This medicine contains an important and useful components, as it consists of Cefuroxime (as axetil).
ZINNAT 125mg is available in the market in concentration 125mg/Tablet and in the form of Tablets.

GLAXO is the producer of ZINNAT 125mg and it is imported from UK, The most popular alternatives of ZINNAT 125mg are listed downward .

Mode Of Action

Cefuroxime binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.

Indication

  • Pharyngitis
  • Acute otitis media
  • Lyme disease
  • Susceptible infections
  • Sinusitis
  • Otitis media
  • Skin and skin structure infections
  • Tonsillitis
  • Respiratory tract infections
  • Acute Maxillary Sinusitis
  • Urinary tract infections
  • Acute bacterial exacerbation of chronic bronchitis
  • Surgical Prophylaxis

Precaution

Severe renal impairment; pregnancy, lactation; hypersensitivity to penicillins. Lactation: Drug excreted in breast milk; use with caution

Side Effects

  • >10% Diarrhea (4-11%; depends on duration) 1-10% Decreased hemoglobin or hematocrit (10%)
  • Eosinophilia (7%)
  • Nausea or vomiting (3-7%)
  • Vaginitis (<5%)
  • Transient rise in hepatic transaminases (2-4%)
  • Diaper rash (3%)
  • Increase in alkaline phosphatase (2%)
  • Thrombophlebitis (2%)
  • Increase in lactate dehydrogenase (1%) <1% Anemia
  • Cholestasis
  • Colitis
  • Dyspnea
  • Epidermal necrolysis
  • Increase in blood urea nitrogen (BUN) and creatinine
  • Jaundice
  • Nephritis
  • Prolonged prothrombin time (PT)/international normalized ratio (INR)
  • Rash
  • Stevens-Johnson syndrome
  • Stomach cramps
  • Transient neutropenia and leukopenia
  • Urticaria Potentially Fatal: Anaphylaxis
  • nephrotoxicity
  • pseudomembranous colitis.

Contra indication

Hypersensitivity to cephalosporins.

Pregnancy and lactation

Pregnancy category: B

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Interaction

May enhance the nephrotoxic effect of strong-acting diuretics (e.g. furosemide) and aminoglycosides. May enhance the effect of oral anticoagulants. May reduce the efficacy of OCs. Probenecid prolongs the excretion of cefuroxime and elevated peak serum level.

Alternatives Price List

  • ZINOXIMOR 500UAD 85
  • ZINOXIMOR 250UAD 50
  • ZINNAT 500mgUAD 91
  • ZINNAT 250mg/5mlUAD 45
  • ZINNAT 250mg/5mlUAD 65

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