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ZESTRIL 10mg Price

Active Substance: Lisinopril (as dihydrate).

66
UAD , based on 7541 reviews.
View Drug details

Overview

Welcome to Dwaey, specifically on ZESTRIL 10mg Tablets page.
This medicine contains an important and useful components, as it consists of Lisinopril (as dihydrate).
ZESTRIL 10mg is available in the market in concentration 10mg/Tablet and in the form of Tablets.

ASTRAZENECA UK LIMITED is the producer of ZESTRIL 10mg and it is imported from UK, The most popular alternatives of ZESTRIL 10mg are listed downward .

Mode Of Action

Lisinopril competitively inhibits ACE from converting angiotensin I to angiotensin II (a potent vasoconstrictor) resulting in increased plasma renin activity and reduced aldosterone (a hormone that causes water and Na retention) secretion. This promotes vasodilation and BP reduction.

Indication

  • Heart failure
  • Myocardial infarction
  • Diabetic nephropathy
  • Hypertension

Precaution

Hypovolaemia, hyperkalaemia, collagen vascular disease, valvular stenosis; before, during or immediately after anaesthesia, preexisting renal insufficiency, unilateral renal artery stenosis. Children <6 yr. Assess renal function. May impair ability to drive or operate machinery. Lactation: Not known if excreted into breast milk; not recommended

Side Effects

  • >10% Dizziness (5-12%) 1-10% Cough (4-9%)
  • Headache (4-6%)
  • Hyperkalemia (2-5%)
  • Diarrhea (3-4%)
  • Hypotension (1-4%)
  • Chest pain (3%)
  • Fatigue (3%)
  • Nausea/vomiting (2%)
  • Kidney disease
  • of AMI patients (2%)
  • Rash (1-2%) <1% Immune hypersensitivity reaction
  • Psoriasis
  • Angioedema of the face
  • lips
  • throat; intestinal angioedema
  • Anuria
  • Atrial tachycardia
  • Acute renal failure
  • Arthralgia
  • Alopecia
  • Atrial fibrillation
  • Bone marrow suppression
  • Cutaneous pseudolymphoma
  • Hypersomnia
  • Leukopenia
  • Mood changes
  • Pancreatitis
  • Skin infections Potentially Fatal: Severe hypotension
  • angioedema.

Contra indication

History of angioedema related to previous treatment with ACE inhibitors, hereditary or idiopathic angioedema. Bilateral renal artery stenosis. Pregnancy (2nd or 3rd trimester), lactation.

Pregnancy and lactation

Pregnancy category: D

There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Interaction

May enhance hypotensive effect w/ diuretics. May increase risk of renal function deterioration and decrease antihypertensive effect w/ NSAIDs. May increase serum levels and toxicity of lithium. Increased risk of hyperkalaemia w/ K-sparing diuretics and K supplements. May increase nitritoid reactions of gold Na thiomalate. Potentially Fatal: Increased risk of hypotension, hyperkalaemia and changes in renal function w/ aliskiren in patients w/ diabetes or renal impairment.

Alternatives Price List

  • ZINOPRIL 20mgUAD 45
  • ZINOPRIL 10mgUAD 33
  • ZESTRIL 5mgUAD 30
  • ZESTRIL 20mgUAD 91
  • ZESTRIL 10mgUAD 66

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