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ZENTEL 400mg Price

Active Substance: Albendazole.

8
UAD , based on 7541 reviews.
View Drug details

Overview

Welcome to Dwaey, specifically on ZENTEL 400mg Tablets page.
This medicine contains an important and useful components, as it consists of Albendazole.
ZENTEL 400mg is available in the market in concentration 400mg/Tablet and in the form of Tablets.

GLAXOSMITHKLINE SOUTH AFRICA (PTY) LTD is the producer of ZENTEL 400mg and it is imported from SOUTH AFRICA, The most popular alternatives of ZENTEL 400mg are listed downward .

Mode Of Action

Albendazole sulfoxide (active metabolite), causes selective degeneration of cytoplasmic microtubules in intestinal and tegmental cells of intestinal helminths and larvae; glycogen is depleted, glucose uptake and cholinesterase secretion are impaired and desecratory substances accumulate intracellulary. ATP production decreases, causing energy depletion, immobilisation and worm death.

Indication

  • Helminthiasis
  • Echinococcosis
  • Neurocysticercosis
  • Enterobiasis
  • Ascariasis
  • Hookworm infections
  • Strongyloidiasis
  • Giardiasis
  • Filariasis

Precaution

Monitor blood counts and liver function. Administer within 7 days of start of normal menstruation in women of childbearing age. Adequate nonhormonal contraceptive measures must be taken during and for 1 mth after therapy. Perform liver function tests and blood counts before and every 2 wk during high dose therapy of hydatid disease. Lactation: unknown, use caution.

Side Effects

  • >10% Headache
  • Neurocysticercosis (11%)
  • Hydatid disease (1.3%)
  • Abnormal LFT
  • Hydatid disease (15.6%)
  • Neurocysticercosis (<1%) 1-10% Abdominal pain
  • Hydatid disease (6%)
  • Nausea/vomiting
  • Hydatid disease (3.7%)
  • Neurocysticercosis (6.2%)
  • Dizziness/vertigo
  • Hydatid disease (1.2%)
  • Neurocysticercosis (<1%)
  • Increased intracranial pressure
  • Neurocysticercosis (1%)
  • Meningeal signs
  • Neurocysticercosis (1%)
  • Alopecia (reversible)
  • Hydatid disease (1.6%)
  • Neurocysticercosis (<1%)
  • Fever
  • Hydatid disease (1%) <1% (selected) Rash
  • Urticaria
  • Agranulocytosis
  • Aplastic anemia
  • Bone marrow suppression
  • Granulocytopenia
  • Pancytopenia
  • Thrombocytopenia
  • Hepatitis
  • Acute liver failure
  • Acute renal failure Potentially Fatal: Bone marrow depression.

Contra indication

Pregnancy and lactation. Neonates. Hypersensitivity, liver impairment.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Increased serum concentrations w/ dexamethasone, praziquantel and cimetidine. Decreased serum concentrations w/ aminoquinoline (antimalarials), carbamazepine, phenobarbital, and phenytoin.

Alternatives Price List

  • ZENTILIFE 200mg UAD 5
  • ZENTEL 400mgUAD 8
  • ZENTEL 200mgUAD 8
  • ZENTEL 100mg/5mlUAD 10
  • ALBENDA 400mg/20mlUAD 8

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