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XELODA 500mg Price

Active Substance: Capecitabine.

2174
UAD , based on 7541 reviews.
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Overview

Welcome to Dwaey, specifically on XELODA 500mg page.
This medicine contains an important and useful components, as it consists of
Capecitabineis available in the market in concentration

Name

Capecitabine

Precaution

Hepatic dysfunction, bone marrow suppression, poor nutritional status, warfarin therapy. Child, elderly, prior extensive pelvic radiation or alkylating therapy. Moderate renal impairment; CBC with differential; monitor hepatic and renal function. Discontinue use if intractable diarrhoea, stomatitis, bone marrow suppression or MI develops.

Indication

Breast cancer, Colorectal cancer, Gastric cancer, Oesophageal cancer

Contra indication

History of severe and unexpected reactions to fluoropyrimidine therapy; severe renal impairment; pregnancy, lactation. Hypersensitivity.

Side Effect

10% Diarrhea,Nausea,Anemia,Lymphopenia,Hand and foot syndrome,Edema,Fatigue,Fever,Headache,Pain,Paresthesia,Alopecia,Dermatitis,Abdominal pain,Anorexia,Appetite decreased,Constipation,Dyspepsia,Stomatitis,Vomiting,Neutropenia,Thrombocytopenia,Dyspnea,Bilirubin increased,Eye irritation 1-10% Chest pain,Dermatitis,Pruritus,Rash,Dizziness,Headache,Weakness,Dehydration,Dry mouth,Dyspepsia,Taste disturbance,Back pain Potentially Fatal: Cardiotoxicity, bone-marrow depression and hyperbilirubinaemia.

Pregnancy Category ID

4

Mode of Action

Capecitabine is a prodrug that is converted to fluorouracil following oral administration, which in turn inhibits thymidylate synthetase, blocking the methylation of deoxyuridylic acid to thymidylic acid, interfering with DNA, and to a lesser degree, RNA synthesis.

Interaction

Antacids containing aluminum and magnesium, leucovorin, anticoagulants, phenytoin, allopurinol.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration

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