ULTIBRO BREEZHALER Price
Active Substance: Glycopyrronium (as bromide), Indacaterol (as maleate).
Overview
Welcome to Dwaey, specifically on ULTIBRO BREEZHALER page.
This medicine contains an important and useful components, as it consists of
Glycopyrronium (as bromide), Indacaterol (as maleate)is available in the market in concentration
Name
Indacaterol + Glycopyrronium
Precaution
Concomitant use w/ long-acting beta-agonists or long-acting muscarinic antagonists. Not for the treatment of asthma. Immediately discontinue use if hypersensitivity & paradoxical bronchospasm occurs. Narrow-angle glaucoma, urinary retention, CV disorders (CAD, acute MI, cardiac arrhythmia, HTN), convulsive disorders or thyrotoxicosis, severe renal impairment; hypokalaemia; hyperglycaemia. Pregnancy & lactation.
Indication
Bronchodilator treatment to relieve symptoms in patients with chronic obstructive pulmonary disease (COPD).
Contra indication
Hypersensitivity to indacaterol, glycopyrronium or to any of the excipients of Indacaterol + Glycopyrronium. All LABAs are contraindicated in patients with asthma without use of a long-term asthma control medication Indacaterol/glycopyrrolate is not indicated for the treatment of asthma Use in children: This should not be used in patients <18 years.
Side Effect
1-10% Nasopharyngitis (4.1%),Hypertension (2%),Back pain (1.8%),Oropharyngeal pain (1.6%)
Pregnancy Category ID
0
Mode of Action
Glycopyrronium: Long-acting muscarinic antagonist (LAMA); often referred to as an anticholinergic; produces bronchodilation by inhibiting acetylcholine’s effect on muscarinic receptors in the airway smooth muscle Indacaterol: Long-acting beta2-agonist (LABA); stimulates intracellular adenyl cyclase, causing conversion of ATP to cyclic AMP; increased cyclic AMP levels cause relaxation of bronchial smooth muscle
Interaction
Decreases levodopa effects. Effects may be enhanced by using drugs with antimuscarinic properties or MAOIs concurrently. May antagonise the GI effects of cisapride, metoclopramide and dompeidone. Potentially Fatal: IV admin in the presence of cyclopropane anesth can result in ventricular arrhythmias.
Pregnancy Category Note
Information not available
Adult Dose
Child Dose
Renal Dose
Administration
