TRILEPTAL 300 Price

Overview

Welcome to Dwaey, specifically on TRILEPTAL 300 Tablets/Film-coated page.
This medicine contains an important and useful components, as it consists of Oxcarbazepine.
TRILEPTAL 300 is available in the market in concentration 300mg/Tablet and in the form of Tablets/Film-coated.

NOVARTIS PHARMA AG is the producer of TRILEPTAL 300 and it is imported from SWITZERLAND, The most popular alternatives of TRILEPTAL 300 are listed downward .

Mode Of Action

Oxcarbazepine blocks voltage-sensitive sodium channels, which inhibits repetitive firing, stabilises hyperexcited neuronal membranes and decreases release of synaptic impulses. These effects may prevent the spread of epileptic seizures.

Indication

• Partial seizures
• Generalised tonic-clonic seizures

Precaution

Patient carrying the HLA-B*1502 allele. Avoid abrupt withdrawal. Severe renal and hepatic impairment. Pregnancy. Patient Counselling May impair ability to drive or operate machinery. Monitoring Parameters Monitor seizure frequency, serum Na, symptoms of CNS depression, hypersensitivity reactions, serum levels of concomitant antiepileptic drugs during titration; periodic thyroid function test and CBC. Lactation: Oxcarbazepine and its active metabolite (MHD) are excreted in human milk; milk-to-plasma concentration ratio of 0.5 was found for both Because of the potential for serious adverse reactions in nursing infants, a decision should be made as to whether a mother should discontinue nursing or whether she should discontinue use of the drug, taking into account the drug's importance to the mother

Side Effects

• >10% Dizziness (30-50%)
• Diplopia (30-50%)
• Headache (26-30%)
• Nausea/vomiting (26-30%)
• Nystagmus (26-30%)
• Somnolence (26-30%)
• Ataxia (10-30%)
• Abnormal gait (16-20%)
• Tremor (16-20%)
• Abdominal pain (11-15%)
• Fatigue (11-15%)
• Vertigo (11-15%)
• Vision abnormalities (11-15%) 1-10% Dyspepsia (5-6%)
• Rash (4%)
• Insomnia (2-4%)
• Abnormal thinking (<4%)
• Hyponatremia (1-3%)
• Muscle weakness (1-2%)
• Hypotension (<2%)
• Speech disorder (1%)
• Asthenia

Contra indication

Hypersensitivity. Lactation.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks