TEVAGRASTIM 48 MIU/0.8 ml Price in UAE

Overview

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This medicine contains an important and useful components, as it consists of
Filgrastim is available in the market in concentration

Name

Filgrastim

Precaution

Filgrastim should not be administered within 24 hours before and after chemotherapy. Premalignant or malignant myeloid condition; sickle-cell disease; osteoporotic bone disease; withdraw treatment if there are signs of pulmonary infiltrates. Fluid retention or heart failure. Monitor CBC and platelet count during therapy. Monitor bone density in patients with osteoporosis (long-term treatment). Regular morphological and cytogenic bone-marrow examinations in severe congenital neutropenia. Pregnancy and lactation. Lactation: excretion in milk unknown; use with caution

Indication

Myelosuppressive chemotherapy, Acute Myeloid Leukemia receiving induction or consolidation chemotherapy, Peripheral blood progenitor cell collection and therapy, Severe Neutropenia, Bone marrow transplantation, HIV infection.

Contra indication

Hypersensitivity to E. coli derived proteins, Filgrastim or any component of the product. Myeloid malignancies. Not to be used within 24 hr of cytotoxic chemotherapy admin due to the sensitivity of rapidly dividing myeloid cells. Severe congenital neutropaenia (Kostman's syndrome) with abnormal cytogenetics.

Side Effect

>10% Nausea (57%),Vomiting (57%),Bone pain (22%-33%),Alopecia (18%),Diarrhea (14%),Fever (12%),Fatigue (11%) 1-10% Headache,Anorexia,Chest pain,Cough,Dyspnea,Constipation,Stomatitis,Sore throat,Rash Frequency Not Defined Elevated uric acid,Elevated lactate dehydrogenase,Elevated alkaline phosphatase Potentially Fatal: Pulmonary infiltrates leading to resp failure or acute resp distress syndrome.

Pregnancy Category ID

3

Mode of Action

Filgrastim is a granulocyte-colony stimulating factor which binds to cell surface receptors on haemetopoietic cells thus stimulating the development of granulocytes to increase their migration and cytotoxicity.