Active Substance: Potassium iodide.
Overview
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This medicine contains an important and useful components, as it consists of
Potassium iodideis available in the market in concentration
Iodine (Potassium Iodide)
Pregnancy, lactation. Hyperkalaemia, hyperthyroidism, myotonia congenita, renal function impairment, tuberculosis, hypocomplementemic vasculitis, goiter, autoimmune thyroid disease. Child. Repeated admin not recommended in neonatesdue to risk of hypothyroidism.
Grave's disease, Iodine deficiency disorders, Wound and ulcer cleansing, hyperthyroidism, Superficial wounds, Thyroid storm .
Hypersensitivity. Acute bronchitis (potassium iodide).
Hypersensitivity reactions (urticaria, angioedema, cutaneous haemorrhage, purpura, fever, arthralgia, lymphadenopathy, eosinophilia); goitre, hypothyroidism and hyperthyroidism. Iodism on prolonged use (metallic taste, increased salivation, swelling and inflammation of throat, swollen and irritated eyes, pulmonary oedema, nausea, vomiting, diarrhoea). Potentially Fatal: Fatal periarteritis, ioderma.
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Potassium iodide participates in a complex series of reactions in the thyroid gland to produce thyroid hormones. When used for hyperthyroidism, it rapidly inhibits the release of thyroid hormones via a direct effect on the thyroid gland and inhibits the synthesis of thyroid hormones. Vascularity of the thyroid gland is reduced. When used in radiation emergencies, oral potassium iodide is admin before or promptly after intake of radioactive iodine, blocks thyroidal uptake of radioactive isotopes of iodine, thereby minimizing the risk of radiation-induced thyroid neoplasms.
Concurrent use with antithyroid agents may lead additional hypothyroid effect. Concurrent use with potassium-containing drugs or potassium-sparing diuretics may lead to hyperkalaemia. Potentially Fatal: Concurrent use with lithium salts may lead to additive hypothyroid effect.
Information not available