TEOSYAL RHA KISS Price

Overview

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Name

Typhoid polysaccharide Vaccine

Precaution

Before receiving the **Typhoid Polysaccharide Vaccine**, it is crucial for patients to consult with their healthcare provider to ensure the vaccine is suitable for their individual health condition. Key precautions include: - **Allergic Reactions**: Individuals who have had a severe allergic reaction (e.g., anaphylaxis) to a previous dose of the **typhoid vaccine** or any component of the vaccine (such as **gelatin**, **thimerosal**, or **sodium chloride**) should not receive this vaccine. It's essential to inform your healthcare provider of any known allergies. - **Moderate to Severe Illness**: If an individual is experiencing an acute illness or fever, it is advisable to delay vaccination until the illness has resolved to avoid confusion between the vaccine's side effects and the symptoms of the illness. - **Pregnancy and Breastfeeding**: Although the **Typhoid Polysaccharide Vaccine** is generally considered safe during pregnancy and breastfeeding, it is essential to consult a healthcare provider before administration to assess the potential risks and benefits, particularly if the individual is traveling to regions with high exposure to typhoid fever. - **Immune System Disorders**: People with weakened immune systems, such as those with **HIV/AIDS**, **cancer**, or individuals on **immunosuppressive therapy**, should consult with a healthcare provider before receiving the vaccine, as their immune response may be less robust. - **Previous History of Typhoid Fever**: If a person has already had typhoid fever, they may have some immunity, but it is still recommended to get vaccinated, particularly if traveling to an area with endemic typhoid.

Indication

The **Typhoid Polysaccharide Vaccine** is used to prevent **typhoid fever**, a serious and potentially life-threatening infection caused by the bacterium **Salmonella enterica serotype Typhi**. It is indicated for: - **Prevention of Typhoid Fever**: The vaccine is primarily recommended for individuals at risk of exposure to **typhoid fever**, particularly those traveling to areas where the disease is common. This includes parts of **Asia**, **Africa**, and **Latin America**, where sanitation and water quality may be inadequate. - **High-Risk Individuals**: Individuals working in environments that could expose them to **Salmonella Typhi**, such as **laboratory workers**, **healthcare workers**, or **military personnel** in endemic areas, should receive this vaccine for protection. - **Travel Medicine**: The **Typhoid Polysaccharide Vaccine** is a critical component of **travel vaccinations** for those visiting regions where typhoid fever is endemic or where sanitation and hygiene standards are low.

Contra indication

The **Typhoid Polysaccharide Vaccine** should be avoided in the following conditions: - **Severe Allergic Reaction**: Anyone who has had a severe allergic reaction (e.g., anaphylaxis) to a previous dose of the **typhoid vaccine** or to any of its components should not receive the vaccine. - **Pregnancy**: While there are no known contraindications, the **Typhoid Polysaccharide Vaccine** should be used cautiously during pregnancy, particularly in the first trimester. It is recommended that pregnant women discuss their vaccination needs with their healthcare provider before receiving the vaccine. - **Infants and Young Children**: The **Typhoid Polysaccharide Vaccine** is typically not recommended for children under **2 years of age**, as its safety and efficacy in this age group have not been well established. A different type of vaccine may be used in younger children. - **Acute Illness or Fever**: If an individual is suffering from a moderate or severe illness or has a fever, the vaccine should be delayed until they have recovered, as the immune system might not respond properly.

Side Effect

Most individuals experience only mild side effects following the **Typhoid Polysaccharide Vaccine**, but some may experience more severe reactions. Common and less common side effects include: - **Common Side Effects**: - **Pain at the Injection Site**: A mild to moderate **pain**, **redness**, or **swelling** at the site of the injection is the most common side effect. - **Fever**: A mild fever, usually below 38.5°C, may develop within a few days after the vaccination. - **Fatigue**: Some individuals may experience **tiredness** or **general malaise**. - **Headache**: A mild to moderate headache is a potential side effect. - **Less Common or Severe Side Effects**: - **Severe Allergic Reactions**: Although rare, some individuals may experience an **allergic reaction** to the vaccine, with symptoms such as **difficulty breathing**, **swelling of the face or throat**, **dizziness**, and **hives**. Anaphylaxis is a medical emergency and requires immediate treatment. - **Fainting**: Some people, particularly adolescents, may experience **fainting** after receiving the vaccine, often due to anxiety or stress rather than a direct reaction to the vaccine. - **Joint Pain or Muscle Aches**: Some people may experience transient **joint pain** or **muscle aches**, which usually resolve on their own.

Pregnancy Category ID

3

Mode of Action

The **Typhoid Polysaccharide Vaccine** works by stimulating the immune system to produce protective antibodies against **Salmonella Typhi**, the bacteria responsible for **typhoid fever**. It contains **purified polysaccharide antigens** derived from the surface of the bacteria. - **Immune Response**: The vaccine introduces these antigens into the body, which triggers the immune system to recognize and remember them. The immune system then produces **antibodies** that can specifically target and neutralize the **Salmonella Typhi** bacteria if the person is exposed in the future. - **Long-term Immunity**: Once vaccinated, the body retains a "memory" of these antigens in the form of **memory cells**. These cells quickly respond if exposed to the actual bacteria, providing protection against developing **typhoid fever**. - **No Live Bacteria**: Since the vaccine does not contain live bacteria, it cannot cause the disease it is designed to protect against, making it safe for most individuals.

Interaction

Certain **drug interactions** and conditions may influence the effectiveness or safety of the **Typhoid Polysaccharide Vaccine**: - **Live Vaccines**: The **Typhoid Polysaccharide Vaccine** is an **inactivated vaccine**, meaning it can be administered at the same time as **live vaccines** (such as **measles**, **mumps**, **rubella**). There are no specific interactions that require special scheduling. - **Immunosuppressive Drugs**: Individuals receiving **immunosuppressive treatments** (e.g., chemotherapy, **corticosteroids**, or **biologics**) may have a reduced immune response to the vaccine. In these cases, the vaccine might not provide optimal protection, and additional doses or alternative strategies may be considered. - **Antibiotics**: There is no known significant interaction between the **Typhoid Polysaccharide Vaccine** and **antibiotics**. However, antibiotics should not be used to treat typhoid fever before vaccination, as they may alter the clinical presentation of the disease, leading to confusion about the vaccine's efficacy. - **Other Vaccines**: There is no known negative interaction between the **Typhoid Polysaccharide Vaccine** and other routine vaccines. If multiple vaccines are required, they can be administered at the same time or on different days, as advised by a healthcare provider.

Pregnancy Category Note

Information not available

Adult Dose

The **Typhoid Polysaccharide Vaccine** is typically administered as a **single dose** for adults, but the following considerations are important: - **Single Dose**: The vaccine is usually given as a single **0.5 mL** intramuscular or subcutaneous injection. - **Booster Dose**: A **booster** dose is recommended every **2-3 years** for individuals who are at continued risk of exposure to **Salmonella Typhi**, such as travelers to endemic areas or healthcare workers in certain settings. - **Travelers**: For adults planning to travel to regions where **typhoid fever** is endemic, the vaccine should ideally be given at least **2 weeks** prior to travel to allow the body time to build immunity.

Child Dose

The **Typhoid Polysaccharide Vaccine** is typically not recommended for children under **2 years of age**. For children aged **2 years and older**, the following applies: - **Standard Dose**: The dose for children is typically the same as that for adults: a **single 0.5 mL** dose administered as an **intramuscular** or **subcutaneous** injection. - **Booster**: As with adults, children who remain at risk of exposure to **Salmonella Typhi** may require a **booster dose** every **2-3 years**. Children who are **younger than 2 years of age** may need an alternative vaccine, such as the **oral live attenuated vaccine** (for specific regions and risk groups). Always consult with a pediatrician to ensure the most appropriate vaccination plan.

Renal Dose

No specific dose adjustments are required for individuals with **renal impairment**. However, since the **Typhoid Polysaccharide Vaccine** is a **non-live** vaccine, it is considered safe for individuals with kidney disease. As with any vaccine, individuals with severe kidney disease or those on dialysis should consult their healthcare provider before receiving the vaccine to ensure there are no other contraindications or concerns.

Administration

Information not available