TELFAST D 60mg/120mg Price

Overview

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This medicine contains an important and useful components, as it consists of
Fexofenadine HCl, Pseudoephedrine HClis available in the market in concentration

Name

Fexofenadine Hydrochloride + Pseudoephedrine Hydrochloride

Precaution

Hyperthyroidism; ischaemic heart disease, arrhythmia or tachycardia; occlusive vascular disorders e.g. arteriosclerosis, hypertension or aneurysms; DM and closed-angle glaucoma; renal impairment, prostatic enlargement. Pregnancy; lactation. Lactation: avoid, not known if enters breast milk

Indication

Allergic rhinitis, Hay fever, Urticaria, Sneezing, Runny nose, Hives, Skin rash, Common cold, Allergy, Itchy or watery eyes, Nasal congestion

Contra indication

Severe hypertension, phaeochromocytoma.

Side Effect

1-10% Headache (7.2%),Drowsiness (1.3%),Fatigue (1.3%) Frequency Not Defined CNS depression,Sedation ranging from mild drowsiness to deep sleep (most frequent),Dizziness,Lassitude,Disturbed coordination,Muscular weakness,Restlessness, insomnia, tremors, euphoria, nervousness, delirium, palpitation, seizures is less common,Epigastric distress,Anorexia,Nausea,Vomiting,Diarrhea,Constipation,Cholestasis, hepatitis, hepatic failure, hepatic function abnormality, jaundice is rare,Tachycardia, palpitation ECG changes (eg, widened QRS). Arrhythmias (eg, extrasystole, heart block),Hypotension,Hypertension,Dizziness, sedation, and hypotension may occur in geriatric patients,Dryness of mouth, nose, and throat,Dysuria,Urinary retention,Impotence,Vertigo,Visual disturbances,Blurred vision,Diplopia; tinnitus,Acute labyrinthitis,Tremors,Nervousness,Irritability,Facial dyskinesia,Tightness of the chest,Thickening of bronchial secretions,Wheezing,Nasal stuffiness,Sweating,Chills,Early menses,Toxic psychosis,Faintness,Paresthesia,Agranulocytosis,Hemolytic anemia,Leukopenia,Thrombocytopenia,Pancytopenia,Dysmenorrhea,Dyspepsia,Fatigue,Ischemic colitis (pseudoephedrine)

Pregnancy Category ID

3

Mode of Action

Fexofenadine, an active metabolite of terfenadine, is a competitive peripheral histamine H1-receptor antagonist on effector cells in the GI tract, blood vessels and respiratory tract. Pseudoephedrine is both an alpha-and beta-adrenergic receptor agonist. It causes vasoconstriction via direct stimulation of alpha-adrenergic receptors of the respiratory mucosa. It also directly stimulates beta-adrenergic receptors causing bronchial relaxation, increased heart rate and contractility.

Interaction

Increased risk of hypertension and arrhythmias if given with cardiac glycosides, quinidine or TCAs. Increased risk of vasoconstrictor effects if given with ergot alkaloids or oxytocin. Co-admin with MAOIs may cause hypertensive crisis. Anaesthetics e.g. cyclopropane, halothane and other halogenated anaesthestics; antihypertensive agents.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration