Active Substance: Flumazenil.
Overview
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This medicine contains an important and useful components, as it consists of
Flumazenilis available in the market in concentration
Flumazenil
Should only be used until the effects of neuromuscular blockade have been fully reversed. Risk of raising intracranial pressure, precipitating convulsions or altering cerebral blood flow in patients with head injuries. Increased risk of seizures in high-risk patients. May provoke panic attacks in patient with a history of panic disorder. Hepatic impairment. Pregnancy and lactation. Lactation: Excretion in milk unknown; use with caution
Benzodiazepine-induced sedation,Benzodiazepine overdose
Hypersensitivity. Patients receiving benzodiazepines for control of a potentially life-threatening condition such as status epilepticus and control of intracranial pressure. Severe intoxication with tricyclic and related antidepressants.
>10% Nausea and vomiting (11%) 1-10% Dizziness (10%),Abnormal/blurred vision (3-9%),Agitation (3-9%),Dyspnea (3-9%),Hyperventilation (3-9%),Pain at injection site (3-9%),Xerostomia (3-9%),Diaphoresis (1-3%),Emotional lability (1-3%),Fatigue (1-3%),Headache (1-3%),Paresthesia (1-3%),Tremor (1-3%),Weakness (1-3%) <1% Delirium,Abnormal hearing,Junctional tachycardia,Thick tongue,Tinnitus,Coldness sensation,Generalized seizure
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Flumazenil competitively inhibits the activity at the benzodiazipine recognition site on the GABA/benzodiazepine receptor complex.
Toxic effects with cyclic antidepressants. Reverses effects of benzodiazepines.
Information not available