Active Substance: Cinnarizine.
Overview
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This medicine contains an important and useful components, as it consists of
Cinnarizineis available in the market in concentration
Cinnarizine
Hypotension; pregnancy; lactation; elderly. May impair ability to drive or operate machineries.
Nausea and vomiting, motion sickness, vertigo, meniere's disease, peripheral vascular diseases, cerebrovascular disorders, vestibular disorders
Proven hypersensitivity to the drug. Parkinson's disease. Childn and neonates.
Extrapyramidal symptoms sometimes associated with severe depression. Drowsiness, headache, GI upsets, unsteadiness, headache; rarely skin and hypersensitivity reactions, dry mouth, blurred vision, urinary difficulty or retention, constipation and increased gastric reflux, fatigue. Hypolipidaemic effect.
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Cinnarizine has calcium-channel blocking activity selective for arterial smooth muscle. It also has some antihistamine activity. Cinnarizine acts as a labyrinthine sedative. It also improves microcirculation by reducing ischaemia-induced blood viscosity.
CNS depressant effect enhanced with alcohol. Action potentiated by domperidone. Increased sedative effect w/ CNS depressants or TCAs.
Information not available