Overview

Welcome to Dwaey, specifically on STRACOXIB 100mg Capsules (Hard Gelatin) page.
This medicine contains an important and useful components, as it consists of Celecoxib.
STRACOXIB 100mg is available in the market in concentration 100mg/Capsule and in the form of Capsules (Hard Gelatin).

LIFEPHARMA FZE is the producer of STRACOXIB 100mg and it is imported from UAE, The most popular alternatives of STRACOXIB 100mg are listed downward .

Mode Of Action & Indication

Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor primarily responsible to reduce mediators of pain and inflammation. Its action is due to inhibition of prostaglandin synthesis via inhibition of COX-2.

Indication

• Rheumatoid arthritis
• Osteoarthritis
• Ankylosing spondylitis
• Dysmenorrhea
• Acute pain
• Familial adenomatous polyposis

Precaution

History of GI bleeding; renal/hepatic insufficiency; asthma or allergic disorders; hypertension; monitor Hb or haematocrit levels for signs of anaemia. History of cerebrovascular disease or ischaemic heart disease (IHD). Lactation: Drug enters breast milk; use caution

Side Effects

• >10% Headache (10-16%)
• Hypertension (13%) 1-10% Fever (9%)
• Dyspepsia (8.8%)
• Upper respiratory tract infection (8.1%)
• Arthralgia (7%)
• Cough (7%)
• Vomiting (6%)
• Diarrhea (5.6%)
• Gastroesophageal reflux (5%)
• Sinusitis (5%)
• Abdominal pain (4.1%)
• Nausea (3.5%)
• Back pain (2.8%)
• Insomnia (2.3%)
• Pharyngitis (2.3%)
• Flatulence (2.2%)
• Rash (2.2%)
• Dizziness (2%)
• Peripheral edema (2%) <1% Anemia
• Erythema multiforme
• Exfoliative dermatitis
• Hepatitis
• Jaundice
• Stevens-Johnson syndrome
• Toxic epidermal necrolysis Frequency Not Defined Increased serum asparate aminotransferase concentration Potentially Fatal: Serious skin reactions such as exfoliative dermatitis
• Stevens-Johnson syndrome
• and toxic epidermal necrolysis.

Contra indication

Hypersensitivity including those in whom attacks of angioedema, rhinitis and urticaria have been precipitated by aspirin, NSAIDs or sulfonamides. Severe hepatic impairment; severe heart failure; inflammatory bowel disease; peptic ulcer; renal impairment (creatinine clearance <30 mL/min); pregnancy and lactation.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Pregnancy category: C; D at >30 weeks' gestation (may cause premature closure of ductus arteriosus)