STERILE DOPAMINE HYDROCHLORIDE 200mg/5ml Price in UAE

Overview

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This medicine contains an important and useful components, as it consists of
Dopamine HClis available in the market in concentration

Name

Dopamine Hydrochloride

Precaution

Shock secondary to MI, history of peripheral vascular disease. Correct hypovolaemia before infusion. History of occlusive vascular disease e.g, atherosclerosis, Raynaud's disease, Buerger's disease, diabetic endarteritis; disproportionate increase in diastolic pressure. Pregnancy. Lactation: Unknown whether drug is excreted into breast milk; use caution

Indication

Shock, Acute heart failure, Hypotension

Contra indication

Pheochromocytoma, uncorrected tachyarrhythmias, ventricular fibrillation. Hypersensitivity.

Side Effect

Cardiovascular: Ventricular arrhythmia, atrial fibrillation (at very high doses), ectopic beats, tachycardia, anginal pain, palpitation, cardiac conduction abnormalities, widened QRS complex, bradycardia, hypotension, hypertension, vasoconstriction Respiratory: Dyspnea Gastrointestinal: Nausea, vomiting Metabolic/nutritional: Azotemia Central nervous system: Headache, anxiety Endocrine: Piloerection Ocular: Increased intraocular pressure; dilated pupils Gangrene of extremities has occurred when high doses were administered for prolonged periods or in patients with occlusive vascular disease receiving low doses of dopamine hydrochloride

Pregnancy Category ID

3

Mode of Action

Dopamine stimulates dopaminergic receptors at lower doses producing renal and mesenteric vasodilation while at higher doses stimulate both dopaminergic and ?-adrenergic receptors producing cardiac stimulation and renal vasodilation. It increases heart rate and force of contraction. At low infusion rates vasodilatation occurs in the renal, mesenteric, coronary and cerebral beds. At higher rates vasoconstriction in skeletal muscles and a rise in BP.

Interaction

Cyclopropane and halogenated hydrocarbon anaesthetics may sensitise myocardium to dopamine and precipitate ventricular arrhythmias. MAO inhibitors prolong and increase dopamine effects. Ergots potentiate vasoconstriction action of dopamine. Alpha-blockers unmask dopamine's beta action.