Active Substance: Nateglinide.
Overview
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This medicine contains an important and useful components, as it consists of
Nateglinideis available in the market in concentration
Nateglinide
Geriatric patients, debilitated and malnourished patients; adrenal or pituitary insufficiency, moderate to severe hepatic impairment; severe renal impairment. Monitor glycaemic levels during periods of stress. Pregnancy. Lactation: unsafe
Type 2 DM
Diabetic ketoacidosis; IDDM. Lactation.
1-10% Increased uric acid (10%),Dizziness (4%),Arthropathy (3%),Flu-like syndrome,Weight gain,Hypoglycemia (2%) Frequency Not Defined Diarrhea,Nausea
3
Nateglinide, a nonsulfonylurea hypoglycaemic agent, acts by stimulating insulin release from pancreatic ?-cells to reduce postprandial hyperglycaemia. This action depends on the amount of existing glucose levels.
Increased levels/effects with enzyme inhibitors (e.g. fluconazole). Increased hypoglycaemic effects with salicylates, MAOIs, nonselective beta-blockers, alcohol, NSAIDs. Decreased levels/effects with enzyme inducers (e.g. rifampicin). Decreased hypoglycaemic effects with thiazide diuretics, corticosteroids, thyroid products and sympathomimetic agents.
Information not available