Typhoid Vaccine (live attenuated)

Welcome to Dwaey, specifically on Typhoid Vaccine (live attenuated) page.
This medicine contains important and useful components, as it consists of
Typhoid Vaccine (live attenuated) is available in the market in concentration.

Generic Name of Typhoid Vaccine (live attenuated) - Learn More

Typhoid Vaccine (live attenuated)

Typhoid Vaccine (live attenuated) Precaution - What You Need to Know

Before receiving the live attenuated Typhoid vaccine, patients must consult their healthcare provider to determine its suitability based on their specific health condition. Important precautions include:
- Pregnancy: The live attenuated typhoid vaccine is classified as a Category C vaccine during pregnancy, meaning that there is limited safety data. It should only be administered to pregnant women if the potential benefit outweighs the risks, particularly in regions where the risk of contracting typhoid is high.
- Immunocompromised Individuals: People with weakened immune systems (e.g., those undergoing chemotherapy, organ transplant recipients, or those with HIV/AIDS) should avoid the live vaccine. The weakened virus in the vaccine may not be adequately controlled by a compromised immune system, potentially causing illness.
- Fever or Illness: The vaccine should be delayed if the individual is currently ill with a fever or acute infection. It is generally recommended to wait until the individual recovers from the illness before administering the vaccine.
- Age Considerations: The live attenuated typhoid vaccine is generally recommended for people aged 6 years and older. It may not be suitable for younger children or those with certain health conditions; a healthcare provider should determine the best course of action.
- Travel Considerations: This vaccine is often recommended for travelers to areas with high endemic rates of Typhoid fever. However, it does not guarantee full protection, so patients should also take appropriate precautions like proper food and water hygiene.

Typhoid Vaccine (live attenuated) Indication - Uses and Benefits

The live attenuated Typhoid vaccine is primarily indicated for the prevention of Typhoid fever. Typhoid fever is caused by the bacterium Salmonella enterica serovar Typhi and is contracted through contaminated food or water. The vaccine is recommended for:
- Travelers: Individuals planning to travel to countries or regions where Typhoid fever is endemic, especially in parts of South Asia, Africa, and Latin America.
- High-risk individuals: People working in environments with high exposure to typhoid carriers (e.g., healthcare workers, food handlers) or those in areas with poor sanitation.
- Military Personnel: Those deployed in areas with a known risk of typhoid fever outbreaks.

The vaccine provides active immunization against the disease by stimulating the immune system to produce antibodies against Salmonella Typhi, thus helping to prevent infection if the individual is exposed.

Typhoid Vaccine (live attenuated) Contraindications - Important Warnings

The live attenuated Typhoid vaccine is contraindicated in the following circumstances:
- Severe Allergic Reaction: If the individual has had a severe allergic reaction (e.g., anaphylaxis) to a previous dose of the Typhoid vaccine or any component of the vaccine (such as eggs, which are sometimes present in the vaccine's preparation), they should not receive this vaccine.
- Immunocompromised Conditions: This vaccine should be avoided in individuals with immunocompromised conditions, such as those with HIV/AIDS, cancer, or those undergoing immunosuppressive therapy. The live virus may cause illness in individuals with weakened immune systems.
- Pregnancy: As mentioned earlier, the vaccine should not be administered during pregnancy unless absolutely necessary, and only under the guidance of a healthcare provider.
- Age: The vaccine is not approved for use in children under 6 years of age. The safety and efficacy of the vaccine in this age group have not been established.

Typhoid Vaccine (live attenuated) Side Effects - What to Expect

Common side effects of the live attenuated Typhoid vaccine are generally mild and short-lived:
- Fever: Some patients may develop a mild fever following vaccination.
- Headache: Headaches are a relatively common side effect after vaccination.
- Gastrointestinal Discomfort: Mild stomach upset, nausea, or diarrhea may occur.
- Injection Site Reactions: If the vaccine is administered as an injectable form, patients may experience pain, redness, or swelling at the injection site.

Less common and more severe side effects include:
- Severe Allergic Reactions: Although rare, some individuals may experience an allergic reaction such as urticaria (hives), swelling, or difficulty breathing, which would require immediate medical attention.
- Systemic Reactions: In very rare cases, the live virus in the vaccine may cause mild systemic illness similar to Typhoid fever itself, though this is uncommon.
- Severe Diarrhea or Vomiting: Some individuals may experience severe digestive upset following the vaccine.

Typhoid Vaccine (live attenuated) Pregnancy Category ID - Safety Information

3

Typhoid Vaccine (live attenuated) Mode of Action - How It Works

The live attenuated Typhoid vaccine works by using a weakened (attenuated) form of the Salmonella Typhi bacterium, which is incapable of causing disease in healthy individuals. Once administered, the vaccine stimulates the body’s immune system to mount a defense against the bacterium:
- Activation of Immune System: The live attenuated vaccine triggers the production of antibodies against Salmonella Typhi, providing active immunity.
- Immune Response: The immune system "learns" how to recognize and fight off the Salmonella Typhi bacteria if the individual is exposed in the future, reducing the risk of contracting Typhoid fever.

Unlike inactivated vaccines, which use killed bacteria or viruses, live attenuated vaccines contain a weakened form of the pathogen, which stimulates a more robust and long-lasting immune response.

Typhoid Vaccine (live attenuated) Drug Interactions - What to Avoid

The live attenuated Typhoid vaccine may interact with certain medications and treatments:
- Immunosuppressive Drugs: Medications that suppress the immune system, such as corticosteroids, chemotherapy, or biologic agents, may reduce the effectiveness of the vaccine and increase the risk of adverse effects.
- Antibiotics: Long-term use of antibiotics (especially quinolones or macrolides) may interfere with the live vaccine's effectiveness. It is advisable to avoid antibiotics for several days before and after vaccination.
- Vaccine Interactions: The live typhoid vaccine should not be given simultaneously with other live vaccines (such as the MMR (measles, mumps, rubella) or varicella vaccines). A gap of at least 4 weeks should be maintained between the administration of live vaccines.
- Antimalarial Drugs: There is no significant interaction between the live attenuated Typhoid vaccine and antimalarial drugs, but it is important to check with a healthcare provider to ensure all vaccinations and medications are safe and effective when taken together.

Typhoid Vaccine (live attenuated) Adult Dose - Recommended Dosage

The live attenuated Typhoid vaccine is administered orally, typically in a 4-dose regimen:
- Standard Dose: The vaccine is taken as a capsule that contains the live bacteria in a weakened form.
- Administration: A total of 4 doses are taken one week apart.
- Booster Doses: A booster dose may be required every 3 years for those at continued risk of exposure to Typhoid fever.

Typhoid Vaccine (live attenuated) Child Dose - Dosage for Children

The live attenuated Typhoid vaccine is approved for children aged 6 years and older. The vaccination schedule is the same as for adults, with 4 doses taken one week apart. It is important to consult with a healthcare provider to assess the suitability and timing of the vaccine, particularly for children traveling to regions with a high incidence of Typhoid fever.

Patients should always consult their healthcare provider before receiving the Typhoid vaccine to ensure the appropriate vaccine is chosen based on their individual health status, travel plans, and risk factors. Proper monitoring for side effects and follow-up may be necessary, especially for those at higher risk of complications.

Typhoid Vaccine (live attenuated) Renal Dose - Dosage for Kidney Conditions

There is no specific adjustment required for renal impairment when administering the live attenuated Typhoid vaccine. However, individuals with significant kidney disease or those undergoing dialysis should consult their healthcare provider before receiving the vaccine, as the live bacteria in the vaccine could theoretically pose risks in severely compromised patients.