What is 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P.
20% w/v Glucose Intravenous Infusion B.P. is a hypertonic solution containing 20 grams of glucose (dextrose monohydrate) per 100 ml of sterile water for injection. The 2000 ml plastic bag provides 400 grams of dextrose. This intravenous solution is used in hospitals for providing immediate energy, managing hypoglycemia, supplementing parenteral nutrition, and serving as a vehicle for drug delivery.
- Generic name: Dextrose (D-glucose)
- Concentration: 20% w/v (hypertonic)
- Volume: 2000 ml (2 liters)
- Purpose: Caloric supplementation, emergency glucose supply, drug diluent
Because it is a high-volume hypertonic solution, it is typically administered via a central venous catheter in clinical settings, especially in intensive care, surgery recovery, or nutrition therapy. The large bag volume ensures prolonged glucose delivery without frequent replacement, especially important in long-term parenteral support.
How to use 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P.
This solution should only be used under strict medical supervision due to its high concentration and volume. Proper technique is essential to avoid complications.
- Administration Route: Intravenous (IV), preferably via central venous line due to hyperosmolarity
- Preparation Steps:
- Inspect the bag for leaks, particulates, or discoloration
- Ensure sterile connection to an appropriate IV set
- Label with patient details and intended infusion rate
- Infusion Guidelines:
- Administer slowly using an infusion pump
- Rate adjusted based on clinical indication and patient tolerance
- Frequent monitoring of blood glucose, electrolytes, and hydration status
- Do Not:
- Administer via bolus or intramuscular injection
- Mix with incompatible medications in the same line
Due to the risk of vein irritation and fluid overload, this formulation should be infused cautiously and never through small peripheral veins.
Mode of Action 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P.
Dextrose (glucose) is a monosaccharide that serves as a vital energy source for all cells. When administered intravenously, it enters the bloodstream immediately and is distributed to tissues where it is metabolized to produce ATP through glycolysis and oxidative phosphorylation.
- Cellular Energy:
- Uptake into cells is insulin-mediated (especially in muscle and fat tissue)
- Used in glycolysis and citric acid cycle to generate ATP
- Clinical Utility:
- Corrects hypoglycemia quickly
- Supports metabolic needs during fasting or stress
- Reduces protein catabolism by serving as an alternate energy source
- Additional Actions:
- Promotes glycogen storage in liver and muscles
- Osmotic properties support fluid movement in parenteral nutrition
This mode of action is especially beneficial for critically ill patients requiring non-enteral energy supplementation.
20% w/v GLUCOSE INTRAVENOUS INFUSION B.P. Interactions 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P.
Despite being a basic carbohydrate, intravenous glucose may interact with various drugs and physiological systems, especially in large volumes.
- Insulin:
- Significantly lowers blood glucose levels
- Must be co-administered in diabetic patients or during total parenteral nutrition (TPN)
- Diuretics (e.g., furosemide):
- May potentiate electrolyte disturbances, especially potassium and magnesium loss
- Electrolyte Supplements:
- Potassium often added to avoid hypokalemia due to insulin response
- Drugs with Limited Solubility:
- Some medications are incompatible with dextrose solutions (e.g., phenytoin, amphotericin B)
- Alcohol and Corticosteroids:
- May alter glucose metabolism, requiring careful monitoring
Always consult compatibility charts and pharmacist guidance before mixing or co-administering with other IV drugs.
Dosage of 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P.
The dose of 20% glucose depends on the patient’s metabolic needs, body weight, glucose tolerance, and therapeutic goals. It must be carefully calculated to avoid hyperglycemia and fluid overload.
- Typical Use: Caloric support in patients unable to take oral nutrition, management of hypoglycemia, or part of TPN regimen
- Adults:
- Caloric dose: 3–5 mg/kg/min (adjusted to maintain euglycemia)
- Volume and rate are individualized based on daily fluid and caloric requirements
- Children:
- Dosing must be weight-based and closely monitored
- Excess glucose may cause rebound hypoglycemia or osmotic diuresis
- Maximum Infusion Rate:
- Should not exceed 0.5 g/kg/hour unless insulin is administered concurrently
Close monitoring of blood glucose, serum electrolytes, and hydration status is essential during therapy.
Possible side effects of 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P.
While generally safe under supervision, 20% Glucose IV infusion may produce side effects, especially with rapid administration or prolonged use.
- Metabolic:
- Hyperglycemia, glycosuria
- Hypokalemia (especially if insulin is administered)
- Osmotic diuresis leading to dehydration
- Vascular:
- Phlebitis, thrombosis, and vein irritation
- Extravasation may cause tissue damage
- Fluid Overload:
- Pulmonary edema in susceptible patients (e.g., heart failure, renal insufficiency)
- Others:
- Headache, restlessness, or confusion due to blood sugar fluctuations
- Rare allergic reactions: fever, rash, or chills
Regular monitoring and prompt intervention can significantly reduce these risks.
20% w/v GLUCOSE INTRAVENOUS INFUSION B.P. Contraindications 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P.
Certain conditions contraindicate the use of 20% glucose infusion, either due to the solution’s high glucose content, osmolarity, or fluid volume.
- Absolute Contraindications:
- Known allergy to dextrose
- Severe hyperglycemia (e.g., diabetic ketoacidosis without insulin)
- Intracranial or intraspinal hemorrhage (risk of exacerbating cerebral edema)
- Relative Contraindications:
- Congestive heart failure (risk of fluid overload)
- Severe renal impairment (reduced clearance)
- Uncorrected electrolyte imbalances (particularly low potassium or magnesium)
Each patient should be carefully evaluated prior to administration, particularly in acute care settings.
Storage of 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P.
Proper storage maintains the efficacy and sterility of the product.
- Temperature: Store below 25°C
- Protection: Keep away from sunlight and freezing conditions
- Packaging Integrity:
- Use only if the plastic bag is intact, clear, and free of particulates
- Do not use if the solution is discolored
- After Opening:
- Use immediately after opening
- Discard any unused portion; do not re-sterilize
- Shelf Life: Refer to product label for expiry date
Always follow institutional protocols for storage, handling, and disposal of medical solutions.
20% w/v GLUCOSE INTRAVENOUS INFUSION B.P. features an exceptional active ingredient renowned for its potent effects, comprising Dextrose. This powerful formulation provides a superior solution for addressing diverse health concerns. With 200mg/ml concentration and an easily manageable Infusion/Solution for, it remains a preferred option for countless individuals seeking effective treatment.
Introduction
All you need to know about 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P. .
Welcome to Dwaey, specifically on 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P. page.
This medicine contains an important and useful components, as it consists of Dextrose.
20% w/v GLUCOSE INTRAVENOUS INFUSION B.P. is available in the market in concentration 200mg/ml and in the form of Infusion/Solution for.
QATAR PHARMA is the producer of 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P. and it is imported from QATAR,
The most popular alternatives of 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P. are listed downward .
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Frequently Asked Questions
20% w/v GLUCOSE INTRAVENOUS INFUSION B.P. should be stored according to the instructions provided by QATAR PHARMA.
In general, it is recommended to store 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P. in a cool, dry place, away from direct sunlight
and out of the reach of children.
The duration of treatment with 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P. may vary depending on the condition being treated
and the guidance of your healthcare provider. It is important to follow the prescribed treatment
plan and continue taking 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P. for the recommended duration, even if your symptoms improve.
If you have any concerns or questions about the duration of treatment, consult your healthcare provider.
It is important to check with your healthcare provider or read the medication label for specific
instructions regarding alcohol consumption while taking 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P. . Some medications, including
20% w/v GLUCOSE INTRAVENOUS INFUSION B.P. , may have interactions with alcohol that can reduce effectiveness, increase side
effects, or pose other risks to your health. It is best to follow the guidance provided by your
healthcare professional.
If you miss a dose of 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P. , take it as soon as you remember. However, if it is close
to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing
schedule. Do not take a double dose to make up for a missed one unless advised by your healthcare provider.
No, do not stop taking 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P. without consulting your healthcare provider, even if your
symptoms improve. It is important to complete the full course of treatment as prescribed. Stopping
the medication prematurely may lead to a relapse or incomplete resolution of the condition. If you
have concerns about the duration of treatment, consult your healthcare provider for guidance.
It is important to consult your healthcare provider before taking 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P. if you are
pregnant or breastfeeding. They will be able to assess the potential risks and benefits based on your
specific situation. Please note that the safety and suitability of 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P. during pregnancy
or breastfeeding may depend on the active substance [Active Substance], concentration 200mg/ml,
and the specific recommendations of QATAR PHARMA.
The effects of 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P. on your ability to drive or operate machinery can vary depending on
the active substance [Active Substance], concentration 200mg/ml, and individual factors.
Some medications may cause drowsiness, dizziness, or other side effects that can impair your judgment
or coordination. It is important to read the medication label or consult your healthcare provider to
understand any potential effects on your ability to perform tasks that require alertness.
The instructions for taking 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P. with or without food may vary depending on the medication
and the recommendations of QATAR PHARMA. Some medications may be more effective when taken with
food to enhance absorption or reduce stomach irritation, while others may need to be taken on an empty
stomach for optimal absorption. Read the medication label or consult your healthcare provider for specific instructions.
The use of 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P. in children or elderly individuals may depend on various factors, including
the specific medication, type Infusion/Solution for, and the recommendations of QATAR PHARMA. Some
medications may have specific dosing instructions or precautions for these age groups. Consult your
healthcare provider or read the medication label for information regarding the safe and appropriate use
of 20% w/v GLUCOSE INTRAVENOUS INFUSION B.P. in children or elderly individuals.
Dwaey
All medical information published on the Dwaey website aims to increase medical awareness and health education among users. However, it is not a substitute for professional medical advice. Always consult with a specialist doctor. We strongly advise against using any information or medicine found on the site without referring to your healthcare provider.
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