What is 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P.
10% w/v Glucose Intravenous Infusion B.P. is a sterile, non-pyrogenic solution containing 10 grams of glucose (as dextrose monohydrate) per 100 mL of water for injection. Supplied in a 100 mL plastic infusion bag, it is classified as a hypertonic solution primarily used in clinical settings to provide energy (calories), correct hypoglycemia, and support fluid replacement.
- Generic Name: Dextrose Monohydrate
- Concentration: 10% w/v (10 g per 100 mL)
- Form: Solution for Intravenous Infusion
- Volume: 100 mL Plastic Infusion Bag
- Osmolarity: Approx. 555 mOsm/L
- pH: 3.5 to 6.5 (approximately)
This glucose solution is used for:
- Supplying immediate energy in patients unable to consume calories orally
- Treating or preventing hypoglycemia (low blood glucose levels)
- Providing hydration and supporting metabolic needs during fasting or recovery
- Acting as a vehicle for compatible intravenous drugs
It is commonly used in hospitalized patients, especially those undergoing surgery, trauma care, or those with metabolic disturbances. It should always be administered under the supervision of a healthcare provider due to potential risks associated with improper dosing or infusion rates.
How to use 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P.
This solution is intended for intravenous (IV) administration only. Proper technique and monitoring are essential to ensure safety and efficacy.
- Route: Intravenous infusion, either peripheral or central depending on patient condition and duration of therapy
- Volume per Use: Varies by individual need; can be given as a bolus or continuous infusion
- Frequency: As prescribed; often used once or multiple times daily depending on glucose/calorie needs
Instructions for Use:
- Inspect the bag for clarity, particulate matter, and leaks before use
- Use only sterile equipment when setting up the IV infusion
- Do not use if the solution appears discolored or cloudy
- Regulate the infusion rate using a controlled infusion pump or drip set
- Monitor the infusion site frequently for signs of irritation or infiltration
Monitoring:
- Check blood glucose levels regularly, especially in patients with diabetes or insulin resistance
- Monitor electrolyte levels, particularly sodium and potassium
- Watch for signs of fluid overload (e.g., edema, increased blood pressure)
The solution should not be administered simultaneously with blood products or incompatible drugs. Compatibility and stability with other substances should be confirmed before co-infusion.
Mode of Action 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P.
Dextrose (glucose) is a monosaccharide carbohydrate that serves as the body’s primary source of energy. When administered intravenously, it bypasses the gastrointestinal tract and enters directly into the bloodstream.
- Immediate Absorption: Glucose is rapidly distributed into extracellular fluid and then into cells via insulin-mediated uptake
- Cellular Metabolism: Inside cells, glucose undergoes glycolysis, producing ATP (adenosine triphosphate), which fuels various cellular functions
- Storage: Excess glucose is stored as glycogen in the liver and muscles or converted to fat in adipose tissue
The solution plays critical physiological roles, including:
- Providing caloric energy for basic metabolic needs
- Preventing ketosis and protein catabolism during fasting or post-operative recovery
- Restoring blood glucose levels in hypoglycemic states
- Acting as a carrier for other IV medications that require dilution
In cases of fluid loss, the hypertonic nature of the solution also draws water into the intravascular space, supporting circulatory volume and blood pressure. However, due to its high osmolarity, careful administration is required to avoid vascular irritation or electrolyte imbalances.
10% w/v GLUCOSE INTRAVENOUS INFUSION B.P. Interactions 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P.
While 10% Glucose IV Infusion is generally safe, it may interact with other drugs or conditions that affect glucose metabolism, fluid balance, or electrolyte regulation.
- Insulin: Enhances cellular uptake of glucose. Co-administration may require dose adjustments to avoid hypoglycemia.
- Corticosteroids: May cause hyperglycemia by reducing glucose tolerance. Monitor blood sugar levels closely.
- Diuretics (e.g., furosemide, thiazides): Can increase the risk of electrolyte imbalances when used concurrently.
- Potassium Supplements (e.g., KCl): Often co-administered to prevent hypokalemia caused by insulin-driven potassium shifts.
- Antiepileptics (e.g., phenytoin): May be incompatible due to pH; use separate IV lines or consult compatibility charts.
Incompatibilities may occur with:
- Blood products – avoid simultaneous administration
- Strongly alkaline drugs – may precipitate or inactivate glucose
- Certain antibiotics and electrolytes – stability may be affected
Always consult with a pharmacist or use an IV compatibility resource when planning to mix or co-administer with other medications.
Dosage of 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P.
Dosage must be individualized based on the patient’s clinical status, age, weight, and caloric requirements. The goal is to supply adequate glucose while minimizing risks such as hyperglycemia or fluid overload.
- Adults: Usually 500–1000 mL/day, depending on caloric needs and fluid status. Not to exceed 3 g/kg/day unless under strict monitoring.
- Children: Typically 10–20 mL/kg/day; higher doses may be required for energy support in pediatric intensive care.
- Neonates/Infants: 50–100 mL/kg/day; infusion rates should be carefully titrated.
Maximum infusion rate:
- In adults: Not more than 0.5 g/kg/hour to avoid osmotic diuresis or glycosuria
- In children: Slower rates are recommended, especially in neonates due to immature renal function
Dosage must be reduced in patients with diabetes, renal failure, or impaired cardiac function. Monitoring is essential to adjust therapy in real time.
Possible side effects of 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P.
Most side effects are dose-related and can be avoided with appropriate monitoring. However, the following adverse reactions may occur:
- Hyperglycemia: Most common in diabetic or insulin-resistant patients
- Glycosuria: Excretion of glucose in urine when renal threshold is exceeded
- Fluid overload: Can lead to pulmonary edema or congestive heart failure in susceptible individuals
- Electrolyte imbalances: Hypokalemia or hyponatremia may develop due to dilution or insulin action
- Phlebitis or thrombophlebitis: Especially if administered through peripheral veins
- Infection risk: From improper handling or contamination of IV lines
Rare allergic reactions such as rash, itching, or anaphylaxis may occur, though these are extremely uncommon. Any signs of discomfort, swelling, or difficulty breathing should prompt immediate medical evaluation.
10% w/v GLUCOSE INTRAVENOUS INFUSION B.P. Contraindications 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P.
This solution is contraindicated in several conditions where its administration may worsen the patient’s status:
- Severe hyperglycemia without concurrent insulin therapy
- Diabetic coma if not under control
- Severe dehydration with electrolyte imbalance (e.g., hyponatremia)
- Fluid overload states: Congestive heart failure, pulmonary edema, or anuria
- Intracranial or intraspinal hemorrhage: Hyperosmolar solutions may exacerbate cerebral edema
- Allergy or intolerance to dextrose or components of the infusion bag
Caution is also advised in patients with renal impairment, liver dysfunction, or those at risk of refeeding syndrome.
Storage of 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P.
To preserve the safety and effectiveness of the product, proper storage conditions must be maintained:
- Storage Temperature: Store below 25°C (77°F). Do not freeze.
- Light Protection: Protect from direct sunlight. Store in the original outer carton.
- Shelf Life: Typically 24–36 months unopened, depending on manufacturer
- Do Not Use If: Solution is cloudy, contains precipitate, or the bag is leaking
Once opened or connected to an IV line, the infusion should be completed within 24 hours. Discard any unused portion. Always follow institutional and manufacturer guidelines for handling and disposal.
10% w/v GLUCOSE INTRAVENOUS INFUSION B.P. features an exceptional active ingredient renowned for its potent effects, comprising Dextrose. This powerful formulation provides a superior solution for addressing diverse health concerns. With 100mg/ml concentration and an easily manageable Infusion/Solution for, it remains a preferred option for countless individuals seeking effective treatment.
Introduction
All you need to know about 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P. .
Welcome to Dwaey, specifically on 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P. page.
This medicine contains an important and useful components, as it consists of Dextrose.
10% w/v GLUCOSE INTRAVENOUS INFUSION B.P. is available in the market in concentration 100mg/ml and in the form of Infusion/Solution for.
QATAR PHARMA is the producer of 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P. and it is imported from QATAR,
The most popular alternatives of 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P. are listed downward .
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Frequently Asked Questions
10% w/v GLUCOSE INTRAVENOUS INFUSION B.P. should be stored according to the instructions provided by QATAR PHARMA.
In general, it is recommended to store 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P. in a cool, dry place, away from direct sunlight
and out of the reach of children.
The duration of treatment with 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P. may vary depending on the condition being treated
and the guidance of your healthcare provider. It is important to follow the prescribed treatment
plan and continue taking 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P. for the recommended duration, even if your symptoms improve.
If you have any concerns or questions about the duration of treatment, consult your healthcare provider.
It is important to check with your healthcare provider or read the medication label for specific
instructions regarding alcohol consumption while taking 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P. . Some medications, including
10% w/v GLUCOSE INTRAVENOUS INFUSION B.P. , may have interactions with alcohol that can reduce effectiveness, increase side
effects, or pose other risks to your health. It is best to follow the guidance provided by your
healthcare professional.
If you miss a dose of 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P. , take it as soon as you remember. However, if it is close
to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing
schedule. Do not take a double dose to make up for a missed one unless advised by your healthcare provider.
No, do not stop taking 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P. without consulting your healthcare provider, even if your
symptoms improve. It is important to complete the full course of treatment as prescribed. Stopping
the medication prematurely may lead to a relapse or incomplete resolution of the condition. If you
have concerns about the duration of treatment, consult your healthcare provider for guidance.
It is important to consult your healthcare provider before taking 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P. if you are
pregnant or breastfeeding. They will be able to assess the potential risks and benefits based on your
specific situation. Please note that the safety and suitability of 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P. during pregnancy
or breastfeeding may depend on the active substance [Active Substance], concentration 100mg/ml,
and the specific recommendations of QATAR PHARMA.
The effects of 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P. on your ability to drive or operate machinery can vary depending on
the active substance [Active Substance], concentration 100mg/ml, and individual factors.
Some medications may cause drowsiness, dizziness, or other side effects that can impair your judgment
or coordination. It is important to read the medication label or consult your healthcare provider to
understand any potential effects on your ability to perform tasks that require alertness.
The instructions for taking 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P. with or without food may vary depending on the medication
and the recommendations of QATAR PHARMA. Some medications may be more effective when taken with
food to enhance absorption or reduce stomach irritation, while others may need to be taken on an empty
stomach for optimal absorption. Read the medication label or consult your healthcare provider for specific instructions.
The use of 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P. in children or elderly individuals may depend on various factors, including
the specific medication, type Infusion/Solution for, and the recommendations of QATAR PHARMA. Some
medications may have specific dosing instructions or precautions for these age groups. Consult your
healthcare provider or read the medication label for information regarding the safe and appropriate use
of 10% w/v GLUCOSE INTRAVENOUS INFUSION B.P. in children or elderly individuals.
Dwaey
All medical information published on the Dwaey website aims to increase medical awareness and health education among users. However, it is not a substitute for professional medical advice. Always consult with a specialist doctor. We strongly advise against using any information or medicine found on the site without referring to your healthcare provider.
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