What is DEXILANT 30mg
DEXILANT 30mg (generic name: Dexlansoprazole) is a medication belonging to the class of proton pump inhibitors (PPIs). It is primarily used to treat conditions associated with excessive stomach acid, such as gastroesophageal reflux disease (GERD), non-erosive reflux disease, and for the healing and maintenance of erosive esophagitis. DEXILANT is distinctive because of its dual delayed-release formulation, which allows two separate releases of medication at different times, providing extended acid suppression and prolonged symptom relief.
- Generic Name: Dexlansoprazole
- Form: Hard Gelatin Capsules (Modified Release)
- Strength: 30 mg per capsule
- Packaging: 28 capsules (7s blister x 4)
- Main Indications: Treatment and maintenance therapy for GERD and erosive esophagitis.
This medicine is especially beneficial for patients who require consistent, long-term control of stomach acid levels.
How to use DEXILANT 30mg
For optimal effectiveness, DEXILANT 30mg should be used according to the prescribed guidelines:
- Administration: Take the capsule orally, with or without food, as directed by your healthcare provider.
- Swallow Whole: Do not crush, chew, or split the capsule. The unique dual delayed-release mechanism requires the capsule to remain intact.
- Alternative Use: If you have difficulty swallowing, you can open the capsule and sprinkle its contents onto a tablespoon of applesauce. Swallow immediately without chewing.
- Consistency: It is recommended to take DEXILANT at the same time each day for better acid suppression.
Follow your doctor's instructions closely. Never change your dose or frequency without consulting your healthcare professional.
Mode of Action DEXILANT 30mg
DEXILANT 30mg acts through a highly specialized pharmacological mechanism:
- Proton Pump Inhibition: Dexlansoprazole irreversibly inhibits the H+/K+ ATPase enzyme located on gastric parietal cells, preventing the final step in acid production.
- Dual Delayed-Release System: The capsule contains two types of granules that release Dexlansoprazole at different times, resulting in an initial and a secondary peak of drug concentration.
- 24-Hour Coverage: This innovative release pattern ensures extended acid suppression, maintaining symptom relief throughout the day and night.
By decreasing gastric acid secretion, DEXILANT promotes healing of the esophageal lining and alleviates symptoms such as heartburn and acid regurgitation.
DEXILANT 30mg Interactions DEXILANT 30mg
Drug interactions may affect how DEXILANT 30mg works or increase the risk of side effects:
- Antifungal Drugs: Medications like ketoconazole, itraconazole, and posaconazole require stomach acid for proper absorption. DEXILANT may reduce their effectiveness.
- Antiviral Agents: Reduced absorption of rilpivirine, atazanavir, and nelfinavir when taken with PPIs.
- Anticoagulants: Dexlansoprazole may alter the effect of warfarin, necessitating close INR monitoring.
- Clopidogrel: May decrease clopidogrel’s antiplatelet effect, requiring careful risk-benefit evaluation.
- Digoxin: Increased digoxin blood levels, leading to potential toxicity, may occur with concurrent PPI use.
Always inform your doctor about all prescription drugs, over-the-counter medications, and supplements you are taking before starting DEXILANT.
Dosage of DEXILANT 30mg
The dosing recommendations for DEXILANT 30mg vary based on the condition being treated:
- Non-Erosive GERD: 30 mg orally once daily for 4 weeks.
- Maintenance of Erosive Esophagitis Healing: 30 mg orally once daily to maintain healing and prevent recurrence of symptoms.
- Special Considerations: No dose adjustment is generally needed in renal impairment. However, caution is advised in severe hepatic impairment.
- Missed Dose: If a dose is missed, take it as soon as you remember. If it’s near the time of your next dose, skip the missed dose. Do not double the dose to catch up.
Always follow your physician’s specific dosage and treatment plan to ensure the best therapeutic outcomes.
Possible side effects of DEXILANT 30mg
DEXILANT 30mg is generally well tolerated, but like any medication, it may cause side effects:
- Common Side Effects:
- Diarrhea
- Nausea
- Abdominal pain
- Vomiting
- Flatulence
- Less Common Side Effects:
- Headache
- Upper respiratory tract infections
- Cough
- Serious Side Effects:
- Hypomagnesemia (muscle spasms, seizures, arrhythmias)
- Clostridium difficile-associated diarrhea
- Bone fractures (particularly with long-term use)
- Vitamin B12 deficiency (long-term therapy)
Seek medical attention immediately if you experience signs of a severe allergic reaction, such as rash, swelling, or difficulty breathing.
DEXILANT 30mg Contraindications DEXILANT 30mg
DEXILANT 30mg should not be used in the following cases:
- Hypersensitivity: Patients allergic to dexlansoprazole, other PPIs, or any component of the product.
- Concomitant Use with Rilpivirine-Containing Products: This combination is contraindicated due to significant interactions leading to reduced efficacy of rilpivirine.
Use with caution in patients with severe liver disease or those who have conditions that predispose to magnesium deficiency or osteoporosis.
Storage of DEXILANT 30mg
Proper storage of DEXILANT ensures its stability and effectiveness:
- Temperature: Store at 20°C to 25°C (68°F to 77°F).
- Protection: Keep the capsules in their original blister pack until use to protect from moisture and light.
- Safety: Keep out of reach of children and pets.
- Do Not Use: After the expiry date printed on the packaging. If capsules appear damaged or discolored, discard them appropriately.
Do not store in the bathroom or other humid environments. Dispose of unused medicine according to local regulations or consult your pharmacist for guidance.
DEXILANT 30mg features an exceptional active ingredient renowned for its potent effects, comprising Dexlansoprazole. This powerful formulation provides a superior solution for addressing diverse health concerns. With 30mg/Capsule concentration and an easily manageable Capsules (Hard Gelatin)/Modified Release, it remains a preferred option for countless individuals seeking effective treatment.
What is Dexilant?
It relieves symptoms of heartburn, difficulty swallowing, and persistent cough. It helps reduce damage from stomach acids, helps prevent ulcers, and may help prevent esophageal cancer. Dexlansoprazole belongs to a class of drugs known as proton pump inhibitors.
The effect of the drug lasts longer than lansoprazole, and therefore it is taken in smaller doses during the day to give complete protection from stomach acids throughout the day.
What are the uses of Dexilant?
It is used to treat erosive esophagitis and gastroesophageal reflux disease by decreasing the production of stomach acids.
What are the contraindications of using Dexilant ?
Liver diseases and a deficiency of liver enzymes responsible for the body s metabolism and getting rid of drugs after a certain period
Colitis
Osteoporosis
bone fractures
Low levels of magnesium in the blood
Allergy to any of the ingredients of the drug
What are the interactions of Dexilant?
Products that may interact with this drug is: methotrexate (especially high-dose therapy). Some products require stomach acid in order for the body to absorb them properly.
Dexlansoprazole reduces stomach acid, so it may alter the effectiveness of these products.
Some affected products include ampicillin, atazanavir, nelfinavir, and certain azole antifungals (itraconazole, ketoconazole), among others. Dexlansoprazole is very similar to lansoprazole. Do not use medications containing lansoprazole while using dexlansoprazole. This medication may interfere with certain laboratory tests and may cause false test results. Make sure laboratory personnel know you use this medicine.
How to use Dexilant
Take this medication by mouth as directed by your doctor, usually once daily with or without food.
If you experience symptoms after a meal, your doctor will immediately advise you to take the dose before the meal for best results.
The dosage and duration of treatment are based on your medical condition and response to treatment.
It is recommended to use this medicine regularly to get the most benefit.
To help you remember, take the dose at the same time each day.
Continue to take this medication for the prescribed length of treatment even if you feel better.
FAQs about Dexilant 30 mg
What is Dexilant 30 mg used for?
Dexilant 30 mg is primarily used for the treatment of gastroesophageal reflux disease (GERD) and its associated symptoms. It helps reduce the production of stomach acid, providing relief from heartburn, regurgitation, and other discomfort caused by GERD. Dexilant is also prescribed for the healing of erosive esophagitis, a condition characterized by inflammation and damage to the lining of the esophagus.
What is the best time of day to take Dexilant?
Dexilant can be taken at any time during the day, with or without food. However, it is generally recommended to take Dexilant before a meal, preferably in the morning. By taking it before breakfast, Dexilant can effectively suppress stomach acid production throughout the day, providing optimal relief from GERD symptoms.
How is Dexilant different from Nexium?
Dexilant and Nexium are both proton pump inhibitors (PPIs) used to treat GERD. However, they contain different active ingredients. Dexilant contains dexlansoprazole, while Nexium contains esomeprazole. Both medications work by reducing stomach acid production, but they have subtle differences in their pharmacokinetics and pharmacodynamics. Dexilant has an extended-release formulation, providing longer-lasting relief compared to immediate-release Nexium. The choice between Dexilant and Nexium should be based on individual response, tolerability, and healthcare professional recommendation.
Can I take Dexilant and omeprazole together?
Combining Dexilant and omeprazole is generally not recommended without medical supervision. Both medications belong to the same class of drugs (PPIs) and have similar mechanisms of action. Taking them together may increase the risk of side effects without offering additional benefits. If you have concerns or need to switch from one medication to another, it is important to consult your healthcare professional for guidance and appropriate dosage adjustments.
What is Dexilant 60 mg used for?
Dexilant 60 mg is a higher dosage strength of the medication and is typically used for specific medical conditions, including the maintenance of healed erosive esophagitis and the long-term management of certain hypersecretory conditions, such as Zollinger-Ellison syndrome. Dexilant 60 mg may be prescribed in cases where a higher level of acid suppression is required.
Dexilant 30 mg price
The price of Dexilant 30 mg is AED 147
Dexilant 30 mg side effects
Common side effects of Dexilant 30 mg may include headache, diarrhea, nausea, abdominal pain, and flatulence. These side effects are usually mild and transient, resolving on their own without specific treatment. However, if any side effects persist or become bothersome, it is important to consult a healthcare professional.
Can I take Dexilant 30 mg twice a day?
Taking Dexilant 30 mg twice a day should only be done under the guidance and supervision of a healthcare professional. The recommended dosage for most adults with GERD is 30 mg once daily. Doubling the daily dosage may increase the risk of side effects without providing additional benefits. It is important to follow the prescribed dosage and consult a healthcare professional for personalized advice based on your specific condition.
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