Active Substance: Sodium bicarbonate.
Overview
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This medicine contains an important and useful components, as it consists of
Sodium bicarbonateis available in the market in concentration
Sodium Bicarbonate
Epilepsy, CHF, renal impairment, liver cirrhosis, hypertension, oedema, eclampsia, aldosteronism. Monitor serum electrolyte concentrations and acid-base status regularly during treatment of acidosis. Pregnancy; lactation.
Dyspepsia, Urine alkalinisation, Severe metabolic acidosis, Hyperkalemia
Metabolic or respiratory alkalosis; hypernatraemia, severe pulmonary oedema; hypocalcaemia, hypochlorhydria.
Aggravated CHF, Cerebral hemorrhage, Edema, Hypernatremia, Hypocalcemia, Hypokalemia, Tetany. Tissue necrosis at inj site.
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Sodium bicarbonate raises blood and urinary pH by dissociation to provide bicarbonate ions, which neutralises the hydrogen ion concentration. It also neutralises gastric acid via production of carbon dioxide.
Increases toxicity of amphetamines, ephedrine, pseudoephedrine, flecainide, quinidine and quinine. Decreases effects of lithium, chlorpropamide and salicylates due to increased clearance. May affect the absorption of certain drugs due to raised intra-gastric pH.
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