SIRDALUD 4mg price in UAE

Overview

Welcome to Dwaey, specifically on SIRDALUD 4mg Tablets page.
This medicine contains an important and useful components, as it consists of Tizanidine (as HCl).
SIRDALUD 4mg is available in the market in concentration 4mg/Tablet and in the form of Tablets.

NOVARTIS PHARMA AG is the producer of SIRDALUD 4mg and it is imported from SWITZERLAND, The most popular alternatives of SIRDALUD 4mg are listed downward .

Mode Of Action

Tizanidine, an alpha2-adrenergic agonist, is a centrally acting muscle relaxant structurally related to clonidine. It reduces spasticity by increasing presynaptic inhibition of motor neurons and has no direct effect on skeletal muscle, the neuromuscular junction or on monosynaptic spinal reflexes.

Indication

Spasticity
Painful muscle spasm

Precaution

Hepatic or renal insufficiency. Children, elderly, pregnancy and lactation. Monitor LFT regularly. Stop treatment if liver enzymes are raised persistently >3 times upper limit of normal range. Avoid abrupt withdrawal of therapy. Lactation: May be excreted in breast milk due to lipophilic nature; use caution

Side Effects

>10% Dry mouth (46-50%)
Somnolence (46-50%)
Dizziness (16-20%)
Asthenia (10-45%) 1-10% Blurred vision (3%)
Constipation (4%)
Infection (6%)
LFT abnormalities (3-5%)
Speech disorder (3%)
Vomiting (3%)
Urinary frequency (3%)
UTI (10%) Frequency Not Defined Asthenia
Bradycardia
Hypotension
Orthostatic hypotension
Syncope (rare) Potentially Fatal: Hepatitis.

Contra indication

Severe hepatic dysfunction.

Pregnancy and lactation

Pregnancy category: C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Interaction

Potentiates hypotensive effect of antihypertensives. Increased CNS effects with alcohol and CNS depressants. Increased bradycardia with ?-blockers and digoxin. Increased serum concentration of tizanidine with CYP1A2 inhibitors e.g. zileuton, ciprofloxacin and other fluoroquinolones, antiarrhythmics, cimetidine, famotidine, oral contraceptives, aciclovir and ticlopidine. Decreased serum concentrations of tizanidine with rifampicin. Use with caution with drugs that may prolong QT interval.