Active Substance: Basiliximab.
Overview
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This medicine contains an important and useful components, as it consists of
Basiliximabis available in the market in concentration
Basiliximab
Pregnancy and lactation. Re-exposure to a subsequent course of therapy of basiliximab. Lactation: Unknown whether excreted in milk; because of the potential for adverse reactions, a decision should be made to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother
Acute graft rejection in renal transplantation
Hypersensitivity to basiliximab and murine proteins.
Peripheral oedema, hypertension, atrial fibrillation; fever, headache, insomnia, pain; wound complication, acne; hypokalaemia, hyperglycaemia, hyperuricaemia, hypophosphataemia, hypercholesterolaemia; GI effects; UTI; anaemia; tremor; dyspnoea, infection. Rarely, hypersensitivity and anaphylactoid-type reactions.
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Basiliximab, a chimeric murine/human monoclonal antibody, blocks the ?-chain of the interleukin-2 receptor complex on the surface of activated T-lymphocytes.
Immunosuppressives other than ciclosporin and corticosteroids may increase the potential for over-immunosuppression.
Information not available