SEVOFLURANE (Shanghai Hengrui) 100 % Price in UAE

Overview

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This medicine contains an important and useful components, as it consists of
Sevofluraneis available in the market in concentration

Name

Sevoflurane

Precaution

Patient w/ increased intracranial pressure, neuromuscular disease (esp Duchenne muscular dystrophy), mitochondrial disorders. Patient who are hypovolaemic, hypotensive, haemodynamically compromised, at risk of QT prolongation. Hepatic and renal impairment. Childn. Pregnancy and lactation. Patient Counselling May impair ability to drive or operate machinery. Monitoring Parameters Monitor for BP, temp, heart rate and rhythm, oxygen saturation, end-tidal CO2, and end-tidal drug concentrations prior to and throughout anaesthesia. Monitor the temp of CO2 absorbent canister. Recovery from general anaesthesia should be assessed carefully before discharge. Lactation: excreted in breast milk; no adverse effect on nursing infant

Indication

General anaesthesia

Contra indication

Known or suspected susceptibility to malignant hyperthermia. Previous hypersensitivity.

Side Effect

Cardiorespiratory depression, hypotension, bradycardia; laryngospasm, increased cough and salivation; urinary retention, acute renal failure, changes in liver enzyme values, liver damage; nausea, vomiting, delirium, seizure; rash, urticaria, pruritus, dyspnoea, wheezing, chest discomfort, bronchospasm, anaphylactic/anaphylactoid reaction; agitation, dystonic movements (childn). Potentially Fatal: Malignant hyperthermia. Rarely, hyperkalaemia resulting in cardiac arrhythmias, particularly in childn w/ neuromuscular disease.

Pregnancy Category ID

2

Mode of Action

Sevoflurane is a volatile halogenated general anaesthetic which causes a reversible loss of consciousness and pain sensation, suppression of voluntary motor activity, modification of autonomic reflexes, depression of the respiratory and CV systems. It also has muscle relaxant properties.

Interaction

May enhance effect and duration of competitive neuromuscular blockers. Metabolism and toxicity increased by cytochrome P450 isoenzyme CYP2E1 inducers including isoniazid and alcohol. Increased risk of cardiac arrhythmias when used with epinephrine or norepinephrine.