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SEROFLO 250 Price

Active Substance: Fluticasone propionate, Salmeterol (as xinafoate).

105
UAD , based on 7541 reviews.
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Overview

Welcome to Dwaey, specifically on SEROFLO 250 page.
This medicine contains an important and useful components, as it consists of
Fluticasone propionate, Salmeterol (as xinafoate)is available in the market in concentration

Name

Salmeterol + Fluticasone

Precaution

Pulmonary TB, severe cardiovascular disorders, heart rhythm abnormalities, DM, thyrotoxicosis, hypokalaemia. Patients at risk of decreased bone mineral content (e.g. smoking, old age, sedentary lifestyle, poor nutrition, family history of osteoporosis or long term use of drugs that may decrease bone mass (e.g. anticonvulsants and corticosteroids). Do not stop therapy abruptly; therapy should be down titrated. Advise patient to rinse mouth after inhalation. Monitor height of children on prolonged therapy. Pregnancy, lactation.

Indication

Chronic Asthma, COPD

Contra indication

Not for primary treatment of status asthmaticus or other acute attacks of asthma. Severe hypersensitivity to milk proteins.

Side Effect

>10% Upper respiratory tract infection (21-27%),Headache (12-21%),Pharyngitis (10-13%) 1-10% Candidiasis, nonspecific site (0-10%),Throat irritation (7-9%), Musculoskeletal pain (2-9%), Bronchitis (2-8%),Upper respiratory inflammation (4-7%),Viral respiratory infections (4-6%),Nausea or vomiting (4-6%),Cough (3-6%),Sinusitis (4-5%),Hoarseness or dysphonia (2-5%),Fever (3-4%),Diarrhea (2-4%),Gastrointestinal (GI) discomfort or pain (1-4%),Oral candidiasis (1-4%),Muscle cramps or spasms (3%),Malaise or fatigue (2-3%),Viral GI infections (0-3%) Potentially Fatal: Paradoxical bronchospasm.

Pregnancy Category ID

3

Mode of Action

Salmeterol, a long acting beta 2-agonist which acts locally in the lung to mediate bronchodilation. Fluticasone, a corticosteroid with mainly glucocorticoid activity, reduce symptoms and exacerbations of asthma.

Interaction

Increased fluticasone levels with CYP 3A4 inhibitors e.g ritonavir, ketoconazole, itraconazole. Additive effects with other beta-agonist.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration

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