SANDIMMUN NEORAL 25mg Price in UAE

Overview

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This medicine contains an important and useful components, as it consists of
Ciclosporinis available in the market in concentration

Name

Dexpanthenol

Precaution

<ul> <li>Use with caution in patients with known hypersensitivity to pantothenic acid derivatives.</li> <li>Avoid contact with eyes if using topically.</li> <li>Monitor for signs of allergic reaction when administered parenterally.</li> <li>Not intended for deep wounds or infected skin without medical supervision (topical).</li> </ul>

Indication

<ul> <li>Prevention and treatment of pantothenic acid deficiency.</li> <li>Supportive therapy in postoperative or post-traumatic ileus (parenteral use).</li> <li>Wound healing and skin regeneration (topical use).</li> <li>Treatment of diaper rash, minor burns, abrasions (topical).</li> </ul>

Contra indication

<ul> <li>Hypersensitivity to dexpanthenol or any component of the formulation.</li> </ul>

Side Effect

<ul> <li>Rare allergic reactions (e.g., rash, itching, redness).</li> <li>Injection site irritation (if given parenterally).</li> <li>Topical: Skin irritation, burning, or contact dermatitis (rare).</li> </ul>

Pregnancy Category ID

Information not available

Mode of Action

Dexpanthenol is the alcohol analog of pantothenic acid (vitamin B5). After administration, it is rapidly converted into pantothenic acid in the body, which is a component of coenzyme A (CoA), essential in cellular metabolism and energy production. It promotes epithelialization and wound healing.

Interaction

<ul> <li>No significant drug interactions are known.</li> <li>May interfere with diagnostic tests based on pantothenic acid levels.</li> </ul>

Pregnancy Category Note

Generally considered safe for use during pregnancy (Category A in topical forms). Systemic use should be limited to when clearly needed and under medical supervision.

Adult Dose

<ul> <li>Parenteral (Postoperative Ileus): 250 mg IM or slow IV once daily.</li> <li>Topical: Apply 1–5% cream/ointment to affected area 1–4 times daily.</li> </ul>

Child Dose

<ul> <li>Topical: Safe in children; apply 1–5% cream/ointment to the affected area 1–3 times daily.</li> <li>Parenteral: Use only under medical supervision; dosage adjustment based on age and weight.</li> </ul>

Renal Dose

No specific dose adjustment needed, but use cautiously in patients with severe renal impairment.

Administration

<ul> <li>Parenteral: Administer IM or slow IV injection. Use sterile technique. Do not mix with other injectable solutions.</li> <li>Topical: Apply a thin layer to clean, dry skin. Gently massage until absorbed. Avoid mucous membranes unless indicated.</li> </ul>