ROZLET 2.5mg Price

Overview

Welcome to Dwaey, specifically on ROZLET 2.5mg page.
This medicine contains an important and useful components, as it consists of
Letrozole is available in the market in concentration

Name

Letrozole

Precaution

Severe renal impairment; severe hepatic impairment; osteoporosis. Caution when driving or operating machinery. Lactation: not known if excreted in breast milk (for post-menopausal women)

Indication

Breast cancer

Contra indication

Premenopausal women and children; hypersensitivity.

Side Effect

Hot flushes, arthralgia, nausea, vomiting, fatigue, dizziness, headache, dyspepsia, constipation, diarrhoea, anorexia, alopoecia, increased sweating, rash, peripheral oedema, osteoporosis, musculoskeletal pain, vaginal irritation. Potentially Fatal: Thromboembolic events.

Pregnancy Category ID

5

Mode of Action

Letrozole competitively binds to the heme group of aromatase, a cytochrome P450 enzyme which catalyzes conversion of androgen to oestrogen, leading to inhibition of the enzyme and a significant reduction in plasma oestrogen levels.

Interaction

Plasma levels reduced by tamoxifen.

Pregnancy Category Note

Information not available

Adult Dose

Child Dose

Renal Dose

Administration