ROCALM Price
Active Substance: Rocuronium bromide.
Overview
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This medicine contains an important and useful components, as it consists of
Rocuronium bromideis available in the market in concentration
Name
Rocuronium Bromide
Precaution
Patient w/ biliary tract disease, neuromuscular disease, previous poliomyelitis, burn injury, severe electrolyte disturbances, Eaton-Lambert syndrome, myasthenia gravis, CV disease, resp disease, pulmonary HTN; obese patients. Renal and hepatic impairment. Elderly. Pregnancy and lactation. Monitoring Parameters Monitor heart rate, BP, twitch response, assisted ventilation status. Lactation: not known if excreted in breast milk; effect on nursing infant not known
Indication
Endotracheal intubation, Aid controlled ventilation, Muscle relaxant in general anesthesia
Contra indication
Hypersensitivity.
Side Effect
1-10% Transient hypotension (1-2%),Hypertension (1-2%) <1% Dose-related tachycardia,Apnea,Abnormal ECG,Injection site edema,Hiccups,Pruritus,Nausea,Wheezing,Residual muscle weakness,Allergic or idiosyncratic hypersensitivity reactions Potentially Fatal: Abnormal ECG, arrhythmia, bronchospasm, anaphylaxis and malignant hyperthermia.
Pregnancy Category ID
3
Mode of Action
Rocuronium is a competitive neuromuscular blocker that acts by blocking the binding of acetylcholine to receptors on the motor endplate, inhibiting depolarisation.
Interaction
May cause enhanced block when used with lidocaine, procainamide, quinidine, verapamil, aminoglycosides, inhalational anaesthetics and vancomycin. May cause prolonged paralysis when used with clindamycin. Anticholinesterases such as pyridostigmine and galantamine may antagonise the effect of rocuronium. Chronic use of carbamazepine or phenytoin may lead to resistance to rocuronium.
Pregnancy Category Note
Information not available
Adult Dose
Child Dose
Renal Dose
Administration
